Projects per year
Personal profile
Personal profile
Dr. Cheng joined the Academy of Pharmacy at XJTLU as an assistant professor in Sep. 2021. She has broad experience in mass spectrometry and NMR-based comprehensive metabolomics and lipidomics studies. She has also been working on biomarker discovery and patient stratification via integrated study of multi-omics data, and investigating the regulatory mechanism of bioactive compounds on health and metabolic disease risk in intervention studies. Contact me via email (ken.cheng@xjtlu.edu.cn) if you are interested in collaboration with us.Research key words:metabolomics, multi-omics, mass spectrometry, biomarker, bioactive compounds in natural products
Research interests
Exploration of novel biomarkers and establishment of diagnostic and predictive models based on multiple omics data, especially metabolome, proteome and gut microbiota, and multi-dimensional data integration approaches.
Regulatory mechanism investigation of bioactive compounds in metabolic diseases.
Mass spectrometry-based analytical methods for comprehensive coverage of metabolome and lipidome.
Experience
Assistant professor, Academy of Pharmacy, XJTLU, Suzhou, 2021-present
Honorary Academic Staff, University of Liverpool, 2021-present
Senior researcher, Shenzhen Digital Life Institute (iCarbonX), Shenzhen, 2018-2021
Postdoc, Department of Food and Nutrition Science, Chalmers Institute of Technology, Goteborg (Sweden), 2017-2018
French translator, I-TEK, Tremeur (France), 2012
Teaching
APH001, Explore Pharmaceutical Sciences (module leader)
APH002, Introduction to Basic Science of Medicine (module leader)
APH004, Brief History of Drug Discovery (module leader)
APH402, Modern Instrumentation Analytical Technologies
APH404, Modern Pharmaceutical Activity Screening
Awards and honours
Shenzhen Longhua Chinese Dragon Plan Talent (level A), 2019
Shenzhen Overseas High-Caliber Personnel (level C), 2019
The Eurofed Lipid Nordic Lipidforum Young Scientist Award, 2017
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Bsc, Harbin Institute of Technology, Harbin, China, 2005-2009
Master, Universite de Rennes, Rennes, France, 2009-2012
PhD, Swedish University of Agricultural Science, Uppsala, Sweden, 2012-2017
Person Types
- Staff
Fingerprint
Collaborations and top research areas from the last five years
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Jiangsu Province Higher Education Key Laboratory of Cell Therapy Nanoformulation (Construction)
Ruan, G., Lee, M. H., Wu, Q., Lu, T., Xu, P., Loo, S., Sun, Y., Kam, A., Liu, X., Wen, X., Zhang, J., Wang, M., Xu, M., Cheng, K., Zhang, X., Song, J., Guo, B., Wang, Y., Wang, J., Wu, S., Yang, J., Fu, L., Zhang, J., Qiao, Y., Chen, Y., Li, T., Huang, D., Gu, J., Zhan, T., Wan, Y., He, Z., Cheng, Y., Leng, J., Qi, M., Ho, J., Sun, Y., Zhang, N., Soe, H. M. S. H., Ling, C. & Zhou, H.
1/07/24 → 30/06/27
Project: Governmental Research Project
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The role of dimethylguanidino valeric acid (DMGV) in carbohydrate and lipid metabolism
1/09/22 → 31/08/25
Project: Internal Research Project
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Study on the mechanism of DMGV-induced functional impairment of pancreatic β-cell and early progression of type 2 diabetes
1/01/25 → 31/12/27
Project: Governmental Research Project
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The mechanism of ammonia accumulation promotes liver cancer progression via calcium channel-mTORC2-SREBP1-lipogenesis dependent manner
Dai, W., Wang, S., Chen, G., Elkord, E., Hamada, K., Cheng, K., Xu, J., Huang, S., Yang, C., Ma, J. & Bin, U.
1/01/25 → 31/12/28
Project: Governmental Research Project
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NSFC General Program: The mechanism of ammonia accumulation promotes liver cancer progression via calcium channel-mTORC2-SREBP1-lipogenesis dependent manner
Dai, W., Hamada, K., Elkord, E. & Cheng, K.
1/01/25 → 31/12/28
Project: Governmental Research Project
File
Research output
- 12 Article
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Effects of Protein on Green Tea Quality in a Milk-Tea Model during Heat Treatment: Antioxidant Activity, Foaming Properties, and Unbound Small-molecule Metabolome.
Chen, N., Jiao, Z., Xie, K., Liu, J., Yao, P., Luo, Y., Zhang, T., Cheng, K. & Zhao, C., 7 Sept 2024, (Accepted/In press) In: Journal of Dairy Science.Research output: Contribution to journal › Article › peer-review
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Flavonifractor plautii Protects Against Elevated Arterial Stiffness
Luo, S., Zhao, Y., Zhu, S., Liu, L., Cheng, K., Ye, B., Han, Y., Fan, J. & Xia, M., 20 Jan 2023, In: Circulation Research. 132, 2, p. 167-181 15 p.Research output: Contribution to journal › Article › peer-review
Open Access17 Citations (Scopus) -
An LC-QToF MS based method for untargeted metabolomics of human fecal samples
Cheng, K., Brunius, C., Fristedt, R. & Landberg, R., 1 Apr 2020, In: Metabolomics. 16, 4, 46.Research output: Contribution to journal › Article › peer-review
Open Access29 Citations (Scopus) -
The polyamine transporter Slc18b1(VPAT) is important for both short and long time memory and for regulation of polyamine content in the brain
Fredriksson, R., Sreedharan, S., Nordenankar, K., Alsiö, J., Lindberg, F. A., Hutchinson, A., Eriksson, A., Roshanbin, S., Ciuculete, D. M., Klockars, A., Todkar, A., Hägglund, M. G., Hellsten, S. V., Hindlycke, V., Västermark, Å., Shevchenko, G., Olivo, G., Cheng, K., Kullander, K., Moazzami, A., & 3 others , 2019, In: PLoS Genetics. 15, 12, e1008455.Research output: Contribution to journal › Article › peer-review
Open Access19 Citations (Scopus) -
Impact of Reduced Dietary Levels of Eicosapentaenoic Acid and Docosahexaenoic Acid on the Composition of Skin Membrane Lipids in Atlantic Salmon (Salmo salar L.)
Cheng, K., Bou, M., Ruyter, B., Pickova, J., Ehtesham, E., Du, L., Venegas, C. & Moazzami, A. A., 22 Aug 2018, In: Journal of Agricultural and Food Chemistry. 66, 33, p. 8876-8884 9 p.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus)