Projects per year
Personal profile
Personal profile
Dr. Shining Loo joined the Academy of Pharmacy at Xi’an Jiaotong-Liverpool University as an Assistant Professor in 2023. Dr. Loo received First-Class Honors in a Double Bachelor’s Degree in Biomedical Science and Traditional Chinese Medicine (TCM) from the Nanyang Technological University (NTU), School of Biological Sciences (SBS), Singapore, and the Beijing University of Chinese Medicine, Beijing, China. She is also a licensed practicing TCM physician in Singapore. She was awarded the prestigious Nanyang President’s Graduate Scholarship and received her Ph.D. in Biological Sciences at NTU, SBS, Singapore, under the supervision of Professor James P. Tam (2013-2018). Upon graduation, Dr. Loo was appointed as a Research Fellow and continued her postdoctoral research work with Professor Tam’s group (2018-2023).Dr. Loo’s research interests center around peptide drug discovery and their translational applications for precision medicine, theranostics, drug delivery, material, and food technologies. Dr. Loo has published over 12 peer-reviewed publications in well-recognized journals like the Journal of American Chemical Society, Journal of Medicinal Chemistry, Journal of Biological Chemistry, Frontiers in Pharmacology, and Frontiers in Plant Sciences. She also holds 2 US and China national phase patent applications. In 2021, Dr. Loo won the Mistletoe Research Fellowship, the title of Mistletoe Research Fellow, and an Unfettered Research Grant from the Momental Foundation. She was also awarded the Merck Life Science Publication Award (First Prize) for her research contributions in the field of biology and biochemistry. Dr. Loos current research focusses on creating a toolbox of cell-penetrating peptides through scaffold innovations for undruggable intracellular molecular targets. This approach has led to the design and discovery of novel peptide-based precision medicines and targeted-drug delivery agents for different diseases. Moreover, these reagents are also applicable as chemical tools in basic science research to improve our understandings on cell signaling.To achieve these objectives, her laboratory employs multidisciplinary approaches including peptide and protein chemistry, molecular pharmacology, mass spectrometry-based proteomics, high-throughput screening, combinatorial libraries, chemical biology, and animal studies. She welcomes interested academic and industrial collaborations as well as students to join her group.Interested parties can contact via e-mail: Shining.loo@xjtlu.edu.cn
Read more about our XPad XJTLU Peptide and Drug research group!
Research interests
Precision Medicine
Peptide Drug Discovery and Design
Mass Spectrometry Proteomics-based Target-identification, Functional and Structural Characterization
High-throughput Drug Screening and Validation
Peptide and Protein Chemistry
Molecular Pharmacology
Targeted Protein Modifiers
Targeted Drug Delivery
Natural Products
Experience
Assistant Professor, Academy of Pharmacy, Xi’an Jiaotong-Liverpool University (2023- Present)
Research Fellow (Supervisor: Professor James P Tam), School of Biological Sciences, Nanyang Technological University, Singapore (2018-2023)
Teaching
APH005 Diseases, Healthcare and Society
APH216 Drug Action
APH303 Biotechnological Pharmaceutics
Awards and honours
XJTLU SURF 2023 Group Winner (2023)
Merck Life Science Publication Award (First Prize) (2021)
Mistletoe Research Fellowship (2021)
10th International Peptide Symposium Travel Award (JPY$ 46,000) (2018)
Women in Engineering, Science, and Technology (WiEST) Conference Grant (SGD$ 3,000) (2018)
Pharmaceuticals Travel Award (CHF$ 800) (2018)
ASBMB Graduate Travel Award (USD$ 1,000) (2018)
Peptide Therapeutics Foundation Travel Grant (USD$ 500) (2016)
Nanyang Presidents Graduate Scholarship (2013-2018)
NTU President Research Scholar (URECA) (2009-2010)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Related documents
Education/Academic qualification
Doctor of Philosophy (Supervisor: Professor James P Tam), School of Biological Sciences, Nanyang Technological University, Singapore (2018)
Bachelor of Medicine (Chinese Medicine), Beijing University of Chinese Medicine, Beijing, China (2012)
Bachelor of Science (Honors- First Class), School of Biological Sciences, Nanyang Technological University, Singapore (2012)
Person Types
- Staff
Fingerprint
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Collaborations and top research areas from the last five years
Projects
- 1 Active
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Multi-targeting cell-penetrating peptide dendrimers: A Versatile Toolset for Cancer Therapy and Diagnostics
1/01/24 → 31/12/26
Project: Internal Research Project
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Broad-spectrum ginsentides are principal bioactives in unraveling the cure-all effects of ginseng
Loo, S., Kam, A., Dutta, B., Zhang, X., Feng, N., Sze, S. K., Liu, C. F., Wang, X. & Tam, J. P., Feb 2024, In: Acta Pharmaceutica Sinica B. 14, 2, p. 653-666 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Ultrafast Biomimetic Oxidative Folding of Cysteine-rich Peptides and Microproteins in Organic Solvents
Kam, A., Loo, S., Qiu, Y., Liu, C. F. & Tam, J. P., 2 Apr 2024, In: Angewandte Chemie - International Edition. 63, 14, e202317789.Research output: Contribution to journal › Article › peer-review
1 Citation (Scopus) -
Broad-spectrum ginsentides are principal bioactives in unraveling the cure-all effects of ginseng
Loo, S., Kam, A., Dutta, B., Tam, J. P., Wang, X., Zhang, X., Liu, C. F., Feng, N. & Sze, S. K., 4 Nov 2023, (Accepted/In press) In: Acta Pharmaceutica Sinica B.Research output: Contribution to journal › Article › peer-review
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Decoding the Cure-all Effects of Ginseng
Loo, S., Kam, A., Dutta, B., Zhang, X., Feng, N., Sze, S. K., Liu, C. F., Wang, X. & Tam, J. P., 7 Apr 2023, In: bioRxiv.Research output: Contribution to journal › Article › peer-review
Open Access -
Editorial on Special Issue “Natural Products for Drug Discovery and Development”
Kam, A. (Guest ed.), Loo, S. (Guest ed.) & Lee, S. M. Y. (Guest ed.), 12 Jun 2023, In: Processes.Research output: Contribution to journal › Editorial
Open Access
Activities
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Pharmaceuticals (Journal)
Shining Loo (Reviewer)
13 May 2024Activity: Peer-review and editorial work of publications › Publication Peer-review
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International Journal of Molecular Sciences (Journal)
Shining Loo (Reviewer)
5 May 2024Activity: Peer-review and editorial work of publications › Publication Peer-review
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International Journal of Molecular Sciences (Journal)
Shining Loo (Reviewer)
20 Apr 2024Activity: Peer-review and editorial work of publications › Publication Peer-review
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Current Issues in Molecular Biology (Journal)
Shining Loo (Associate Editor), Antony Kam (Associate Editor) & Simon M.Y. Lee (Associate Editor)
18 Apr 2024 → …Activity: Peer-review and editorial work of publications › Editorial work
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Current Issues in Molecular Biology (Journal)
Shining Loo (Editor)
3 Apr 2024 → …Activity: Peer-review and editorial work of publications › Editorial work