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20002024

Research activity per year

Personal profile

Personal profile

Minyan Wang joined at XJTLU at Department of Biological Sciences in 2011. She is currently Professor, Director of Centre for Neuroscience jointly founded by Wangwenli Charitable Foundation and XJTLU; She holds an honorary staff position at the University of Liverpool and is PhD supervisor at the Institute of Translational Medicine, University of Liverpool, UK. Prior to her position at XJTLU, she held a lecturer position at the School of Pharmacy and Biomedical Sciences, University of Central Lancashire, UK between 2008-2011, after the two postdoctoral training at University of Newcastle and University of Bradford, UK, During 2004-2008. She was awarded of PhD in Neuropharmacology in 2004 at University of Bradford, UK, and obtained 1st degree in Pharmacy in 1988 and MSc in Pharmacology in 1997 at Hebei Medical University. She has rich experience in curriculum design and development in Higher Education and holds an MA degree in teaching an learning in Higher Education, UK. Her research projects focus on molecular mechanisms of migraine pain and drug target identification. More details about her publications can be found via the URL (https://www.researchgate.net/profile/Minyan_Wang).

Research interests

My main research interest is to understand the molecular basis of migraine. Both cortical spreading depression (CSD), which is associated with the aura phase of migraine and activation of trigeminovascular system are the hallmarks of migraine. To understand the underlying mechanisms of migraine, we have focused on the neuropeptide calcitonin gene-related peptide (CGRP) and key neurotransmitter receptor subunits and ion channels using multi-disciplinary approach. We apply neurobiology approach (e.g., WB, qPCR, IHC, IP), in vitro chick retinal spreading depression and a mouse brain slice CSD models of migraine aura using intrinsic optical imaging; We also have in vivo microdialysis-based rat migraine model using electrophysiology and laser Doppler flowmetry to monitor cerebral blood flow changes. With the development of the Centre for Neuroscience under my direction, we are looking at how CGRP might be induced in early stage of migraine and how key molecules involved in NMDA receptor and TRPA1 signalling mediate cortex susceptibility to CSD challenge and sensory perception. Our research outcome may point to novel prophylactic and therapeutic strategies for migraine and the neurological disorders associated with CSD. For more information on my research, please see my research gate profile.

Experience

Lecturer/Associate Professor/Senior Associate Professor/Professor, XJTLU, 2011 to 2022

Lecturer, School of Pharmacy and Biomedical Sciences, University of Central Lancashire - 2008 to 2010

Senior Pharmacologist and ICT-China project manager, Institute of Cancer Therapeutics , University of Bradford - 2006 to 2008

Postdoctoral Research Fellow, Institute of Neuroscience, University of Newcastle - 2004 to 2006

Visiting Scientist, School of Biomedical Sciences, University of Nottingham - 2000 to 2000

Pharmacologist/Senior Pharmacologist/Pharmacist, Department of Pharmacology, Hebei Medicine Control Institute, a subsector of SFDA - 1988 to 2000

Teaching

Modules taught at XJTLU: Cellular and Molecular Biology; Experimental Design and Analysis; Biochemical Methods and Analysis; Cell Structure and Function; Molecular Biology Principle; Molecular and Cell Biology Techniques; Advanced Biochemical Methods; Final Year Project.

Modules taught in the UK University: Introduction to Biochemistry; Cellular and Biochemical Basis of Pharmacology; Investigation of Diseases; System Pharmacology; CNS, Pain and Cancer Therapy; Cancer Biology

Courses at XJTLU: Biological Sciences (UG); Bioinformatics (UG): Molecular Bioscience (MRes)

Courses in the UK university: Pharmacy(UG); Biomedical Sciences (UG); Cancer Biology (MRes)

Expertise related to UN Sustainable Development Goals

In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):

  • SDG 3 - Good Health and Well-being

Education/Academic qualification

Ph.D. , Neuropharmacology, University of Bradford, UK - 2004

M.Sc. , Pharmacology, Hebei Medical University, China - 1997

B.Sc. , Pharmacy, Hebei Medical University, China - 1988

M.A. , Teaching and learning in higher education, University of Central Lancashire, UK- 2012

Person Types

  • Staff

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