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Personal profile
Personal profile
Minyan Wang joined at XJTLU at Department of Biological Sciences in 2011. She is currently Professor, Director of Centre for Neuroscience jointly founded by Wangwenli Charitable Foundation and XJTLU; She holds an honorary staff position at the University of Liverpool and is PhD supervisor at the Institute of Translational Medicine, University of Liverpool, UK. Prior to her position at XJTLU, she held a lecturer position at the School of Pharmacy and Biomedical Sciences, University of Central Lancashire, UK between 2008-2011, after the two postdoctoral training at University of Newcastle and University of Bradford, UK, During 2004-2008. She was awarded of PhD in Neuropharmacology in 2004 at University of Bradford, UK, and obtained 1st degree in Pharmacy in 1988 and MSc in Pharmacology in 1997 at Hebei Medical University. She has rich experience in curriculum design and development in Higher Education and holds an MA degree in teaching an learning in Higher Education, UK. Her research projects focus on molecular mechanisms of migraine pain and drug target identification.
Research interests
Much of Professor Wang’s work has been in migraine research, but also conducted evaluation of pharmaceutical drugs for treating epilepsy, ischemia, and diabetes. Over the past 2 decades, she has dedicated her career to pioneering research in migraine pathogenesis. Her lab applies neurobiology approach, microdialysis, intrinsic optical imaging, electrophysiology and laser Doppler flowmetry to accurately simulate migraine aura and its pathophysiological events on ex vivo retina and mouse brain slices as well as in vivo rodents. Leading many projects with international collaborations, her work has advanced the understanding of the signaling pathways involved in the pathogenesis of migraines, serving as a foundation for drug target identification. These include researching membrane receptors, calcitonin gene-related Peptide (CGRP), stress-sensing cation channel TRPA1 and intracellular kinases involved in central and trigeminovascular system sensitization. The findings addressed how these signals sensitize the CNS and trigeminal nerve to trigger migraine. She has enriched academic literature with over 35 scholarly papers and book chapters.
More details about her publications can be also found via the URL (https://www.researchgate.net/profile/Minyan_Wang).
Professor Wang cordially invite passionate Ph.D. candidates with an interest in neuroscience to apply for our projects.
Experience
Lecturer/Associate Professor/Senior Associate Professor/Professor, XJTLU, 2011 to 2022
Lecturer, School of Pharmacy and Biomedical Sciences, University of Central Lancashire - 2008 to 2010
Senior Pharmacologist and ICT-China project manager, Institute of Cancer Therapeutics , University of Bradford - 2006 to 2008
Postdoctoral Research Fellow, Institute of Neuroscience, University of Newcastle - 2004 to 2006
Visiting Scientist, School of Biomedical Sciences, University of Nottingham - 2000 to 2000
Pharmacologist/Senior Pharmacologist/Pharmacist, Department of Pharmacology, Hebei Medicine Control Institute, a subsector of SFDA - 1988 to 2000
Teaching
Modules taught at XJTLU: Cellular and Molecular Biology; Experimental Design and Analysis; Biochemical Methods and Analysis; Cell Structure and Function; Molecular Biology Principle; Molecular and Cell Biology Techniques; Advanced Biochemical Methods; Final Year Project.
Modules taught in the UK University: Introduction to Biochemistry; Cellular and Biochemical Basis of Pharmacology; Investigation of Diseases; System Pharmacology; CNS, Pain and Cancer Therapy; Cancer Biology
Courses at XJTLU: Biological Sciences (UG); Bioinformatics (UG): Molecular Bioscience (MRes)
Courses in the UK university: Pharmacy(UG); Biomedical Sciences (UG); Cancer Biology (MRes)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Ph.D. , Neuropharmacology, University of Bradford, UK - 2004
M.Sc. , Pharmacology, Hebei Medical University, China - 1997
B.Sc. , Pharmacy, Hebei Medical University, China - 1988
M.A. , Teaching and learning in higher education, University of Central Lancashire, UK- 2012
Person Types
- Staff
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Collaborations and top research areas from the last five years
Projects
- 4 Finished
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Suzhou Municipal Key Lab for Metabolic Syndrome Drug Research
Meng, J., Meng, W., Jiang, X., Wei, Z., Li, T., Liu, X., Su, J., Yue, C., Douroudis, K., Kappes, F., Park, J., Wang, M., Rong, R., Raju, S., Huang, X., Kadowaki, T., OConnor, D., Lu, Z., Feng, Q., Yi, Y., Chen, Y., Jiang, B., Yuan, X., Cui, J., Meng, S., Smith, G., Loh, B. & 李荪
1/01/22 → 31/12/23
Project: Governmental Research Project
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Identification of drug targets involved in TRPA1 signaling for preventing classical migraine
Wang, M., Wang, M., Kappes, F., Quinn, J., 蒋莉文, 马冬青, 聂聆俤 & 鲁德意
1/07/18 → 30/06/21
Project: Internal Research Project
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Sarcoma family kinase signaling in migraine pathophysiology
1/01/18 → 30/09/21
Project: Internal Research Project
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Migraine mechanism: Cortical Spreading Depression induces CGRP expression involving ROS and TRPA1
1/03/17 → 28/02/20
Project: Internal Research Project
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Gender-different effect of Src family kinases antagonism on photophobia and trigeminal ganglion activity
Huang, Z., Yao, J., Nie, L., Nie, X., Xiong, X., Koks, S., Quinn, J. P., Kanhere, A. & Wang, M., Oct 2024, In: Journal of Headache and Pain.Research output: Contribution to journal › Article › peer-review
Open Access -
Src family kinases (SFKs) in Migraine
Wang, M., Gong, Z. & Huang, Z., 24 Oct 2024, Migraine Pain Management: Current Pharmacological and Non-pharmacological Options. Shrewsbury, S. B. (ed.). 1st Edition ed. Elsevier, Vol. In Part II: Druggable targets.Research output: Chapter in Book or Report/Conference proceeding › Chapter › peer-review
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Src Family Kinases Facilitate the Crosstalk between CGRP and Cytokines in Sensitizing Trigeminal Ganglion via Transmitting CGRP Receptor/PKA Pathway
Nie, L., Sun, K., Gong, Z., Li, H., Quinn, J. P. & Wang, M., Oct 2024, MDPI (Basel, Switzerland) . (Migraine Neuroscience: From Experimental Models to Target Therapy)Research output: Book/Report/Edited volume › Anthology › peer-review
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Transient Receptor Potential Ankyrin 1-dependent Activation of Extracellular Signal-regulated Kinase 2 in the Cerebral Cortices Contributes to Cortical Spreading Depolarization
Li, H., Wang, C., Gong, Z., Nie, L., Xu, J. & Wang, M., 5 Apr 2024, In: Neuroscience. 543, p. 90-100 11 p.Research output: Contribution to journal › Article › peer-review
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A collective statement in support of saving pangolins
Choo, S. W., Chong, J. L., Gaubert, P., Hughes, A. C., O'Brien, S., Chaber, A. L., Antunes, A., Platto, S., Sun, N. C. M., Yu, L., Koepfli, K. P., Suwal, T. L., Thakur, M., Ntie, S., Panjang, E., Kumaran, J. V., Mahmood, T., Heighton, S. P., Dorji, D., Gonedelé, B. S., & 45 others , 10 Jun 2022, In: Science of the Total Environment. 824, 153666.Research output: Contribution to journal › Letter › peer-review
Open Access6 Citations (Scopus)
Activities
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Invited speaker: Plenary lecture
Minyan Wang (Speaker)
23 Sept 2024 → 25 Sept 2024Activity: Talk or presentation › Invited talk
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Role of transient receptor potential ankyrin 1 in light aversion of mice
Minyan Wang (Speaker)
25 Jun 2024 → 29 Jun 2024Activity: Talk or presentation › Presentation at conference/workshop/seminar
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Federation of European Neuroscience Forum
Minyan Wang (Participant), Junyu Yao (Participant), Lingdi Nie (Participant) & Zhuoan Huang (Participant)
25 Jun 2024 → 30 Jun 2024Activity: Participating in or organising an event › Participating in an event e.g. a conference, workshop, …
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