Projects per year
Personal profile
Personal profile
Dr. Daiyun Huang received his BSc degree in Mathematics from the University of Liverpool in 2017, his MSc degree in Statistical Science from the University of Oxford in 2018, and his Ph.D. degree in Computer Science from the University of Liverpool in July 2022. He joined the Academy of Pharmacy at XJTLU as a postdoctoral fellow in November 2022.His previous research revolved around developing deep learning models for biological sequences, especially for RNA modification research. His current research interests mainly focus on AI-aided drug discovery, including developing deep learning methods for high-throughput virtual screening and de novo generation of hit-like molecules. Special attention is paid to out-of-distribution problems and protein representation learning.
Research interests
AI-aided drug discovery: high-throughput virtual screening and de novo generation of hit-like molecules.
Prediction and engineering of non-coding sequences of mRNA-based therapeutics based on deep learning
Develop computational models of biological sequences (DNA, RNA, and proteins) to address meaningful biological questions, such as predicting the effect of mutations on protein function.
Experience
Postdoc, Academy of Pharmacy, Xian Jiaotong-Liverpool University, 2022-present
Teaching
APH101-2223-S2-Biostatistics and R Programming
APH102-2223-S2-Mathematical Modeling
Awards and honours
2022年入选“苏州市自然科学优秀学术论文一等奖”(SZLW202206,2020-2021年度)
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Ph.D., University of Liverpool, 2022
MSc, University of Oxford, 2018
BSc, University of Liverpool, 2017
Person Types
- Staff
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Collaborations and top research areas from the last five years
Projects
- 3 Active
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Jiangsu Province Higher Education Key Laboratory of Cell Therapy Nanoformulation (Construction)
Ruan, G., Lee, M. H., Wu, Q., Lu, T., Xu, P., Loo, S., Sun, Y., Kam, A., Liu, X., Wen, X., Zhang, J., Wang, M., Xu, M., Cheng, K., Zhang, X., Song, J., Guo, B., Wang, Y., Wang, J., Wu, S., Yang, J., Fu, L., Zhang, J., Qiao, Y., Chen, Y., Li, T., Huang, D., Gu, J., Zhan, T., Wan, Y., He, Z., Cheng, Y., Leng, J., Qi, M., Ho, J., Sun, Y., Zhang, N., Soe, H. M. S. H., Ling, C. & Zhou, H.
1/07/24 → 30/06/27
Project: Governmental Research Project
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Prediction and engineering of non-coding sequences of mRNA therapeutics based on deep learning
1/01/24 → 31/12/26
Project: Governmental Research Project
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Research on mitigating cold-protein problem in deep learning-based drug hits virtual screening models
Huang, D., Liu, X., Li, T., Hao, Y., Wang, T., Zha, H., Li, B. & Chen, Y.
1/09/23 → 31/08/26
Project: Governmental Research Project
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Detection and Quantification of 5moU RNA Modification from Direct RNA Sequencing Data
Li, J., Sun, F., He, K., Zhang, L., Meng, J., Huang, D. & Zhang, Y., 2024, In: Current Genomics. 25, 3, p. 212-225 14 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Developing a Semi-Supervised Approach Using a PU-Learning-Based Data Augmentation Strategy for Multitarget Drug Discovery
Hao, Y., Li, B., Huang, D., Wu, S., Wang, T., Fu, L. & Liu, X., Aug 2024, In: International Journal of Molecular Sciences. 25, 15, 8239.Research output: Contribution to journal › Article › peer-review
Open Access -
NanoMUD: Profiling of pseudouridine and N1-methylpseudouridine using Oxford Nanopore direct RNA sequencing
Zhang, Y., Yan, H., Wei, Z., Hong, H., Huang, D., Liu, G., Qin, Q., Rong, R., Gao, P., Meng, J. & Ying, B., Jun 2024, In: International Journal of Biological Macromolecules. 270, 132433.Research output: Contribution to journal › Article › peer-review
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DirectRMDB: a database of post-transcriptional RNA modifications unveiled from direct RNA sequencing technology
Zhang, Y., Jiang, J., Ma, J., Wei, Z., Wang, Y., Song, B., Meng, J., Jia, G., De Magalhães, J. P., Rigden, D. J., Hang, D. & Chen, K., 6 Jan 2023, In: Nucleic Acids Research. 51, D1, p. D106-D116Research output: Contribution to journal › Article › peer-review
Open Access46 Citations (Scopus) -
m6A-Atlas v2.0: updated resources for unraveling the N 6-methyladenosine (m6A) epitranscriptome among multiple species.
Wei, Z., Meng, J., Wang, Y. & Huang, D., 2023, In: Nucleic Acids Research.Research output: Contribution to journal › Article › peer-review