Projects per year
Personal profile
Personal profile
Yi Li is now Associate Professor in the Department of Chemistry at Xian Jiaotong-Liverpool University. He studied for his PhD with Professor Manfred Hesse at the University of Zurich, investigating the synthesis of polyamine alkaloids. He then held Postdoctoral Fellowships with Professor Tony Barrett at Imperial College, London, and Professor Karl Hale, at University College London and Queens University, Belfast. In 2008, Yi Li joined Professor Gerry Pattenden at the University of Nottingham to study the biomimetic synthesis of complex polycyclic diterpenes found in corals. He was first appointed as Lecturer in the Department of Chemistry at Xian Jiaotong-Liverpool University in 2011 and promoted to the current position in 2015. Yi Lis research interests have been in the development of strategies for organic synthesis and total synthesis of biologically active natural products.
Research interests
Organic Synthesis and Natural Products
Natural products have served as the invaluable sources for drug discovery and the inspiration of organic synthesis which remains the cornerstone of future developments in biosciences, materials science, medicine and molecular engineering for decades to come.
My research focuses on the synthetic studies of select natural products of biomedical significance and the development of synthetic methodology for the construction of complex, biologically intriguing molecules.
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Experience
Lecturer, Department of Chemistry, Xiapos;an Jiaotong-Liverpool University, China - 2011 to Present
Research Fellow (with Prof. Gerry Pattenden, FRS), School of Chemistry, University of Nottingham - 2008 to 2011
Postdoctoral Research Fellow (with Prof. Karl Hale), University College London and Queenapos;s University, Belfast - 2004 to 2008
Postdoctoral Research Fellow (with Prof. Tony Barrett, FRS), Department of Chemistry, Imperial College - 2002 to 2004
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
Ph.D. , Organic Chemistry; University of Zürich, Switzerland, - 2002
M.C. , Master of Chemistry; The University of New South Wales, Australia, - 1998
B.S. , Bachelor of Science (Chemistry); Zhengzhou University, China, - 1988
Person Types
- Staff
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Collaborations and top research areas from the last five years
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Development of SQR-targeting, cyclopentenethione-based H2S donors_ Design, synthesis and pharmacodynamics study
1/01/23 → 31/12/25
Project: Internal Research Project
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SIP High-quality Innovation Platform for chronic diseases
Fu, L., Zhang, X., Liu, X., Wang, R., Li, Y., Gu, J., Ruan, G., Chen, J., Zhang, J., Lee, M. H., Wang, Y., Chen, Y., Guo, J., Wang, Y., Hong, M., Yue, Y., Guo, H., Xu, H., Yang, D. & Cheng, J.
1/09/22 → 30/08/25
Project: Governmental Research Project
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Developing visible-light photoredox dual catalysis system and its application in organic synthesis
1/07/18 → 31/03/22
Project: Internal Research Project
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New Methods for the Asymmetric Trifluoromethylation of Organic Molecules
Li, Y., 庞明伦, 武建芳 & 梁岩
1/09/13 → 30/06/17
Project: Governmental Research Project
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Regulators of phagocytosis as pharmacologic targets for stroke treatment
Cheng, J., Wang, W., Xia, Y., Li, Y., Jia, J. & Xiao, G., 2023, In: Frontiers in Pharmacology. 14, 1122527.Research output: Contribution to journal › Review article › peer-review
Open Access1 Citation (Scopus) -
Development of Photoremovable Linkers as a Novel Strategy to Improve the Pharmacokinetics of Drug Conjugates and Their Potential Application in Antibody–Drug Conjugates for Cancer Therapy
Johan, A. N. & Li, Y., Jun 2022, In: Pharmaceuticals. 15, 6, 655.Research output: Contribution to journal › Review article › peer-review
Open Access1 Citation (Scopus) -
Endogenous H2S targets mitochondria to promote continual phagocytosis of erythrocytes by microglia after intracerebral hemorrhage
Li, Y., 2022, In: Redox Biology. 56, 102442.Research output: Contribution to journal › Article › peer-review
14 Citations (Scopus) -
Research progress on insect diversity
Wang, M., Luo, A., Zhou, Q., Chen, J., Xie, T., Li, Y., Chesters, D., Shi, X., Xiao, H., Liu, H., Ding, Q., Zhou, X., Luo, Y., Lu, Y., Tong, Y., Zhao, Z., Bai, M., Guo, P., Chen, S., Nakamura, A., & 13 others , 20 Oct 2022, In: Biodiversity Science. 30, 10, 22454.Research output: Contribution to journal › Article › peer-review
Open Access -
香豆素类化合物的合成方法
Li, Y. & Zhan, K., 26 Mar 2019, Patent No. CN106674175B, 16 Dec 2036Translated title of the contribution :Method for synthesizing coumarin compounds Research output: Patent