@inproceedings{c763be0725e54183abf8ad00af277c7b,
title = "Graph Edge Entropy in Maxwell-Boltzmann Statistics for Alzheimer{\textquoteright}s Disease Analysis",
abstract = "In this paper, we explore how to the decompose the global thermodynamic entropy of a network into components associated with its edges. Commencing from a statistical mechanical picture in which the normalised Laplacian matrix plays the role of Hamiltonian operator, thermodynamic entropy can be calculated from partition function associated with different energy level occupation distributions arising from Maxwell-Boltzmann statistics. Using the spectral decomposition of the Laplacian, we show how to project the edge-entropy components so that the detailed distribution of entropy across the edges of a network can be achieved. We apply the resulting method to fMRI activation networks to evaluate the qualitative and quantitative characterisations. The entropic measurement turns out to be an effective tool to identify the differences in the structure of Alzheimer{\textquoteright}s disease by selecting the most salient anatomical brain regions.",
keywords = "Alzheimer{\textquoteright}s disease (AD), Graph edge entropy, fMRI networks",
author = "Jianjia Wang and Wilson, {Richard C.} and Hancock, {Edwin R.}",
note = "Publisher Copyright: {\textcopyright} 2019, Springer Nature Switzerland AG.; 12th IAPR-TC15 Workshop on Graph-Based Representations in Pattern Recognition, GbRPR 2019 ; Conference date: 19-06-2019 Through 21-06-2019",
year = "2019",
doi = "10.1007/978-3-030-20081-7_6",
language = "English",
isbn = "9783030200800",
series = "Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)",
publisher = "Springer Verlag",
pages = "56--66",
editor = "Donatello Conte and Jean-Yves Ramel and Pasquale Foggia",
booktitle = "Graph-Based Representations in Pattern Recognition - 12th IAPR-TC-15 International Workshop, GbRPR 2019, Proceedings",
}