TY - JOUR
T1 - Facile Fabrication of CuO Nanoparticles Embedded in N-Doped Carbon Nanostructure for Electrochemical Sensing of Dopamine
AU - Sobahi, Nebras
AU - Imran, Mohd
AU - Khan, Mohammad Ehtisham
AU - Mohammad, Akbar
AU - Alam, Md Mottahir
AU - Yoon, Taeho
AU - M. Mehedi, Ibrahim
AU - Hussain, Mohammad A.
AU - Abdulaal, Mohammed J.
AU - A. Jiman, Ahmad
N1 - Publisher Copyright:
© 2022 Nebras Sobahi et al.
PY - 2022
Y1 - 2022
N2 - In the present study, a highly selective and sensitive electrochemical sensing platform for the detection of dopamine was developed with CuO nanoparticles embedded in N-doped carbon nanostructure (CuO@NDC). The successfully fabricated nanostructures were characterized by standard instrumentation techniques. The fabricated CuO@NDC nanostructures were used for the development of dopamine electrochemical sensor. The reaction mechanism of a dopamine on the electrode surface is a three-electron three-proton process. The proposed sensor's performance was shown to be superior to several recently reported investigations. Under optimized conditions, the linear equation for detecting dopamine by differential pulse voltammetry is Ipa (μA) = 0.07701 c (μM) - 0.1232 (R2 = 0.996), and the linear range is 5-75 μM. The limit of detection (LOD) and sensitivity were calculated as 0.868 μM and 421.1 μA/μM, respectively. The sensor has simple preparation, low cost, high sensitivity, good stability, and good reproducibility.
AB - In the present study, a highly selective and sensitive electrochemical sensing platform for the detection of dopamine was developed with CuO nanoparticles embedded in N-doped carbon nanostructure (CuO@NDC). The successfully fabricated nanostructures were characterized by standard instrumentation techniques. The fabricated CuO@NDC nanostructures were used for the development of dopamine electrochemical sensor. The reaction mechanism of a dopamine on the electrode surface is a three-electron three-proton process. The proposed sensor's performance was shown to be superior to several recently reported investigations. Under optimized conditions, the linear equation for detecting dopamine by differential pulse voltammetry is Ipa (μA) = 0.07701 c (μM) - 0.1232 (R2 = 0.996), and the linear range is 5-75 μM. The limit of detection (LOD) and sensitivity were calculated as 0.868 μM and 421.1 μA/μM, respectively. The sensor has simple preparation, low cost, high sensitivity, good stability, and good reproducibility.
UR - http://www.scopus.com/inward/record.url?scp=85141258314&partnerID=8YFLogxK
U2 - 10.1155/2022/6482133
DO - 10.1155/2022/6482133
M3 - Article
AN - SCOPUS:85141258314
SN - 1565-3633
VL - 2022
JO - Bioinorganic Chemistry and Applications
JF - Bioinorganic Chemistry and Applications
M1 - 6482133
ER -