A microfluidic FET biosensor with rolled-up inn microtubes

Pengfei Song, Hao Fu, Yongjie Wang, Cheng Chen, Zetian Mi, Jun Song, Xinyu Liu*

*Corresponding author for this work

Research output: Chapter in Book or Report/Conference proceedingConference Proceedingpeer-review

Abstract

This paper combines two fascinating technologies, the field-effect transistor (FET) biosensor and the rolled-up microtube (RUM), to develop sensitive diagnostic device. We integrated indium nitride (InN) into a rolled-up microtube and use it as the FET channel. Using human immunodeficiency virus (HIV) antibody as a model disease marker, we characterized the analytical performance of the developed biosensor and achieved a limit of detection (LOD) of 100 pg mL-1 for HIV gp41 antibodies detection in buffer solutions. The rolled-up InN microtube FET biosensor represents a new type of III-nitride-based FET biosensor and holds significant potential for practical point of care diagnosis.

Original languageEnglish
Title of host publication22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
PublisherChemical and Biological Microsystems Society
Pages842-843
Number of pages2
ISBN (Electronic)9781510897571
Publication statusPublished - 2018
Externally publishedYes
Event22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018 - Kaohsiung, Taiwan, Province of China
Duration: 11 Nov 201815 Nov 2018

Publication series

Name22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Volume2

Conference

Conference22nd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2018
Country/TerritoryTaiwan, Province of China
CityKaohsiung
Period11/11/1815/11/18

Keywords

  • Biosensor
  • Field-effect-transistor
  • HIV diagnosis
  • Rolled-up microtube

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