Projects per year
Personal profile
Personal profile
Pengfei Song is an associate professor of Mechatronics and Robotics at XJTLU. He earned his B.Eng. from Jilin University (2013) and Ph.D. in Mechanical Engineering from McGill University (2018), focusing on microfluidic biosensors and its instrumentation.
His research focuses on microfluidic biosensors, autonomous microscale robotics, and smart healthcare instrumentation, advancing applications in precision diagnostics, lab-on-a-chip systems, and drug discovery systems. He has published more than 50 SCI journals (H-index 18) in top journals, like Biosensors and Bioelectronics, Lab on a Chip (Cover article) and Analytical Chemistry (Cover article), Microsystems & Nanoengineering, and IEEE-TASE, including impact new findings in AI-empowered automated ELISA platforms and automated C. elegans drug screening platforms.
Pengfei has received multiple awards, including the 2024 Second Prize for Excellent Academic Papers (Suzhou Computer Society), and 2022 IEEE Transactions on Mechatronics Best Paper Finalist. He serves as Associate Editor for IEEE Robotics and Automation Letters and Frontiers in Robotics and AI, and in technical committees for top international conferences like MicroTAS and MARSS.
Research interests
AI-integrated automated paper-based microfluidic systems for diseases diagnostics: Paper-based microfluidics offer portable, low-cost diagnostics but faces problems like environmental variations induced low sensitivity, and low automation. Our recent research efforts are trying to comprehensively address these issues, by 1) designing an automated valving system (IEEE MEMS 2022 and Lab Chip 2025) and 2) utilizing it for multiplex detection (Sens. Actuator B-Chem, 2025); 3) developing one AI-integrated platform that can reduce the external illumination (Anal. Chim. Acta, 2023) with smartphone implementation (Anal. Chim. Acta, 2025), and 4) developing one AI algorithm that can save 33% of sensing time (Anal. Chem. 2025).
AI-integrated automated C. elegans drug screening and microinjection systems: C. elegans is a key model organism for neurodegenerative and aging research, yet manual drug screening remains slow and error-prone. We address these by developing: 1) an automated-microfluidic system for automated microenvironment control and behavior tracking (Biomed. Microdevices, 2020); 2) automated size measurement (IEEE Trans. Nanobiosci., 2022); 3) robotic microinjection for genetic studies (IEEE TASE/ICRA, 2020/2023); and 4) AI-driven multi-parameter screening (Micromachines, 2024). These innovations streamline workflows, enhance precision, and accelerate drug discovery.
Functional nanomaterial synthesis and its sensing applications: Nanocellulose offers biosensing potential with biocompatibility and surface versatility, but its integration into microfluidic systems and unclear sensing mechanisms limit practical applications. Our recent research efforts are trying to address these issues by, 1) developing one microembossing (ACS Appl. Mater. Interfaces 2023) and one laser cutting (IEEE Sensors 2025) methods for creating the microfluidic channel, and was invited for video shooting (JoVE 2024); 2) probing the SERS mechanism on nanocellulose (ACS Appl. Mater. Interfaces 2024), and 3) apply it with AD’s disease screening (Anal. Chim. Acta, 2024).
AI for education: We recognize the irresistible trend of integrating AI into every aspect of our daily lives, including higher education. However, the specific forms in which we should embrace AI remain unknown to all of us, and we are all in the process of exploration. To address this issue, in collaboration with colleagues from the AoFE, we have studied the role of short videos in digital and intelligent education (Humanit. Soc. Sci. Commun. 2022), developed an automated fair allocation scheme for Final Year Project (FYP) topics (Humanit. Soc. Sci. Commun. 2024), and investigated students' perceptions of this (Comput. Hum. Behav., 2023).
Experience
Visiting Doctoral Student, Department of Mechanical and Industrial Engineering - University of Toronto, 2018
Teaching Assistant, Department of Mechanical Engineering - McGill University, 2014 - 2017
Research Assistant, Biomedical Microsystem Laboratory - McGill University, 2013 - 2018
Visiting Research Assistant, Department of Precision Instruments Mechanology - Tsinghua University, 2013
Teaching
SAT 001, Explore Advanced Technology
EEE 116, Experimental, Computer Skills and Sustainability
EEE 001, Introduction to Robotics
EEE 116, Experimental, Computer Skills and Sustainability
EEE 001, Introduction to Robotics
Awards and honours
Backbone of Science and Education in Dushu Lake Science and Education Innovation Zone, Suzhou City
Best Paper Award Finalist and Editors pick article, Journal of Biomicrofluidics
Graduate Research Enhancement and Travel Award (GREAT), McGill University
Best Conference Paper Finalist, IEEE 2015 International Conference on Robotics and Automation
Best Automation Paper Finalist, IEEE 2015 International Conference on Robotics and Automation
NSERC-CREATE ISS Fellowship Award, McGill University
Best Paper Award in Microfluidics Symposium, ASME 2014 International Mechanical Engineering Congress Exposition
Dr. Y Lin-Alexander Fellowship, McGill University
McGill Engineering Doctoral Award (MEDA), McGill University
China Scholarship Council (CSC) Scholarship, Chinese Ministry of Education
National Undergraduate Scholarship, Chinese Ministry of Education
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
B.Eng. in Mechanical Engineering - Jilin University, Changchun, China, 2013
Ph.D. in Mechanical Engineering - McGill University, Montreal, Canada, 2018
Person Types
- Staff
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Collaborations and top research areas from the last five years
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Theoretical construction and empirical research on artificial intelligence promoting the fair distribution of project-based learning resources
Song, P., Li, N., Lim, E. G., Leach, M. & Zhang, X.
1/11/24 → 31/10/27
Project: Governmental Research Project
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Artificial Intelligence Assisted Efficient Carbon Dioxide Photocatalyst Screening and Engineering Education Demonstration
Song, P., Li, N., Lim, E. G., Leach, M., Zhang, X. & Liu, P.
1/07/24 → 1/07/26
Project: Governmental Research Project
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A bioinspired enhanced SERS nanocellulose biosensor
Song, P., Chen, M., Lim, E. G. & Wang, J.
1/10/23 → 30/09/25
Project: Governmental Research Project
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A SERS nanocellulose biosensor based on micro-nano transfer printing technology
Song, P., Lim, E. G., Wang, J. & Chen, M.
1/08/23 → 31/07/25
Project: Governmental Research Project
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Fully automatic paper-based microfluidic POCT platform intellectual property operation guidance plan
Song, P., Lim, E. G. & Yan, J.
1/08/23 → 31/08/25
Project: Governmental Research Project
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An integrated paper-based microfluidic platform for screening of early-stage Alzheimer's disease by detecting Aβ42
Duan, S., Cai, T., Chen, L., Wang, X., Zhang, S., Han, B., Lim, E. G., Hoettges, K., Hu, Y. & Song, P., 2025, (Accepted/In press) In: Lab on a Chip. 25, 4, p. 512-523 12 p.Research output: Contribution to journal › Article › peer-review
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Enhanced sensitivity in acute myocardial infarction diagnosis through optimized multiplex biomarker detection on a paper-based microfluidic platform with individual control capabilities
Chen, L., Duan, S., Cai, T., Xu, D., Hu, Y., Zhang, C., Lim, E. G., Wei, X. & Song, P., 1 Jan 2025, In: Sensors and Actuators B: Chemical. 422, 136616.Research output: Contribution to journal › Article › peer-review
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Facile Laser Cutting Process for Nanocellulose-Paper-Based Microfluidic Microchannel Fabrication
Lu, M., Yuan, W., Yong, R., Yuan, H., Jiang, Z., Gong, Y., Niu, F. & Song, P., 2025, (Accepted/In press) In: IEEE Sensors Journal. 25, 4, p. 6107-6113 7 p.Research output: Contribution to journal › Article › peer-review
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Optimizing light pattern curvature to improve the performance of optoelectronic tweezers in micromanipulation
Xu, B., Li, G., Zheng, L., Dong, W., Song, P., Guo, Z., Li, Z., Liu, H., Ma, Z., Xie, H., Xie, W., Li, H., Fu, R., Lu, Y., Liu, N., Xie, H. & Zhang, S., 27 Jan 2025, In: Optics Express. 33, 2, p. 2968-2979 12 p.Research output: Contribution to journal › Article › peer-review
Open Access -
Sulfur vacancy-rich ZnS on ordered microporous carbon frameworks for efficient photocatalytic CO2 reduction
Gao, X., Li, L., Zhao, Z., Dappe, Y. J., Jiang, Z. J., Song, P., Wang, Y. & Zhu, J., 5 May 2025, In: Applied Catalysis B: Environmental. 364, 124835.Research output: Contribution to journal › Article › peer-review
Activities
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Chemical and Biological Microsystems Society (CBMS) (External organisation)
Pengfei Song (Member)
1 Mar 2024 → …Activity: Membership › Membership of committee
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The 28th International Conference on Miniaturized Systems for Chemistry and Life Sciences -Micro-Total Analysis Systems (µTAS 2024) (Event)
Pengfei Song (Programme Committee Member)
2024 → …Activity: Peer-review and editorial work of publications › Publication Peer-review
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2023 International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS’ 2022), Abu Dhabi, UAE (Event)
Pengfei Song (Programme Committee Member)
9 Oct 2023 → 13 Oct 2023Activity: Peer-review and editorial work of publications › Editorial work
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A fully-automated paper-based microfluidic platform
Pengfei Song (Speaker)
27 Aug 2023Activity: Talk or presentation › Presentation at conference/workshop/seminar
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A bio-inspired lateral flow assay for improving the sensitivity of low volume samples
Pengfei Song (Speaker)
5 Aug 2023Activity: Talk or presentation › Presentation at conference/workshop/seminar