Projects per year
Personal profile
Personal profile
Please call me Kevin :) I received my PhD from City University of Hong Kong in 2017. I completed my postdoctoral training at the College of Pharmacy, Ohio State University, United States (2017-2021). I then worked as a fellow at Shanghai Institute for Advanced Study, Zhejiang University (2021-2024). Meanwhile, I were a postdoctoral researcher at the Institute of Quantitative Biology, College of Life Sciences of Zhejiang University and Center for Precision Medicine of Shenzhen Luohu People’s Hospital. I joined Xi’an Jiaotong-Liverpool University as an Assistant Professor in 2024.
Since my PhD, I have pursued an interdisciplinary research program on the interface of molecular simulation, drug discovery and machine learning. My current research interests are artificial intelligence for biomolecular dynamics (AI4Science) and molecular simulations of various complex biomolecular systems, including the human immunological synapse, the bacterial membrane protein assembly, the CRISPR genome editing tools, and design of molecular glues for protein machinery. I published 20+ high-quality papers in peer-reviewed journal, including Nature, Nature Communications, PNAS, JCIM, JPCB etc. I also actively serve in the academic community as a member of Biophysical Society, American Chemical Society, The Protein Society.
陈骏，博士毕业于香港城市大学物理与材料科学系，其后美国俄亥俄州立大学药学院、浙江大学任博士后、研究员。长期致力于跨学科研究，在分子模拟、药物发现和机器学习等交叉科学领域拥有丰富经验，特别擅长利用分子动力学模拟技术研究复杂生物大分子系统，并应用人工智能技术于复杂体系动力学研究（AI for Science）。在包括Nature, Nature Communications, PNAS, JCIM, JPCB等顶级同行评审科学期刊上发表了多篇高质量研究论文。
Research interests
Artificial intelligence for biomolecular dynamics (AI4Science)
Human immunological synapse
Bacterial membrane protein assembly
CRISPR genome editing tools
Design of molecular glues for protein machinery
Experience
2024-Present - Assistant Professor, Xi'an Jiaotong-Liverpool University, Suzhou, CN
2021-2024 - Postdoc and Fellow, Zhejiang University, Shanghai/Hangzhou, CN
2017-2021 - Postdoc, The Ohio State University, Columbus, US
Teaching
BIO303 Final Year Project
BIO311 Modeling for Computational Biology
Expertise related to UN Sustainable Development Goals
In 2015, UN member states agreed to 17 global Sustainable Development Goals (SDGs) to end poverty, protect the planet and ensure prosperity for all. This person’s work contributes towards the following SDG(s):
Education/Academic qualification
PhD, City University of Hong Kong
2013 → 2017
Keywords
- Q Science (General)
- Molecular dynamics
- Drug discovery and design
- Machine learning
Person Types
- Staff
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Collaborations and top research areas from the last five years
Recent external collaboration on country/territory level. Dive into details by clicking on the dots or
Projects
- 2 Active
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From Static to Dynamic: A Computational Approach to Next-Generation Drug Discovery
1/01/25 → 31/12/27
Project: Internal Research Project
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From Static to Dynamic: A Computational Approach to Next-Generation Drug Discovery
1/01/25 → 31/12/27
Project: Internal Research Project
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In silico design of high-affinity antigenic peptides for HLA-B44
Feng, M., Chan, K. C., Zhong, Q. & Zhou, R., May 2024, In: International Journal of Biological Macromolecules. 267, 131356.Research output: Contribution to journal › Article › peer-review
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A mutagenesis study of autoantigen optimization for potential T1D vaccine design
Song, Y., Bell, D. R., Ahmed, R., Chan, K. C., Lee, S., Hamad, A. R. A. & Zhou, R., 18 Apr 2023, In: Proceedings of the National Academy of Sciences of the United States of America. 120, 16, e2214430120.Research output: Contribution to journal › Article › peer-review
Open Access4 Citations (Scopus) -
Arginine Finger Serving as the Starter of Viral DNA Packaging Motors
Liang, C., Chan, C., Li, Z., Cheng, X. & Guo, P., 1 Jan 2023, Biomotors and their Nanobiotechnology Applications. CRC Press, p. 155-157 3 p.Research output: Chapter in Book or Report/Conference proceeding › Chapter › peer-review
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Conformational cycle of human polyamine transporter ATP13A2
Mu, J., Xue, C., Fu, L., Yu, Z., Nie, M., Wu, M., Chen, X., Liu, K., Bu, R., Huang, Y., Yang, B., Han, J., Jiang, Q., Chan, K. C., Zhou, R., Li, H., Huang, A., Wang, Y. & Liu, Z., Dec 2023, In: Nature Communications. 14, 1, 1978.Research output: Contribution to journal › Article › peer-review
Open Access8 Citations (Scopus) -
Molecular Dynamics Refinement of Open State Serotonin 5-HT3A Receptor Structures
Li, Z., Chan, K. C., Nickels, J. D. & Cheng, X., 27 Feb 2023, In: Journal of Chemical Information and Modeling. 63, 4, p. 1196-1207 12 p.Research output: Contribution to journal › Article › peer-review
Activities
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Antigenic Mimicry in Cross-reactive Recognition through Peptide-MHC Dynamics
Chun Chan (Speaker)
17 Dec 2024Activity: Talk or presentation › Invited talk
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7th Symposium on Biophysics Postgraduate Research in Hong Kong
Chun Chan (Participant)
16 Dec 2024 → 18 Dec 2024Activity: Participating in or organising an event › Participating in an event e.g. a conference, workshop, …
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Exploring Antigenic Mimicry in Cross-reactive Recognition through Peptide-MHC Dynamics
Chun Chan (Speaker)
25 Oct 2024Activity: Talk or presentation › Invited talk
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Antigenic Mimicry in Cross-reactive Recognition through Peptide-MHC Dynamics
Chun Chan (Speaker)
19 Oct 2024Activity: Talk or presentation › Invited talk
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The Second ACS Smart Materials & Engineering International Conference
Chun Chan (Participant)
17 Oct 2024 → 19 Oct 2024Activity: Participating in or organising an event › Participating in an event e.g. a conference, workshop, …