Simultenous voltammetric detection of acetaminophen and tramadol using molybdenum tungsten disulfide-modified graphite screen-printed electrode

Peyman Mohamadzadeh Jahani, Sayed Zia Mohammadi, Ali Khodabakhshzadeh, Mehdi Shahedi Asl, Ho Won Jang, Mohammadreza Shokouhimehr, Kaiqiang Zhang*, Quyet Van Le*, Wanxi Peng*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

13 Citations (Scopus)

Abstract

Nanopetal-structured molybdenum tungsten disulfide (MTD) have been successfully synthesized and applied as a very good modifier for constructing a new and strongly sensitive electro-chemical sensing ground for concurrent detection of two crucial pain reliever medicines, acetaminophen and tramadol. XRD, EDX and SEM have been employed for characterizing synthesized nanoparticles. A comprehensive examination by electro-chemical techniques, including differential pulse voltammetry (DPV) and cyclic voltammetry (CV) has been conducted for clarifying electro-catalytic features of nanopetals by modify graphite screen printed electrode (SPE). Under the optimal condition, the MTD/SPE provided linearly responses in range between 0.04-600.0 and little determination limit of 12.0 nM for acetaminophen. Accurate and sensitive concurrent detection of acetaminophen and tramadol in biological samples and medicine formulations validated the suggested sensor reliability.

Original languageEnglish
Pages (from-to)9024-9036
Number of pages13
JournalInternational Journal of Electrochemical Science
Volume15
Issue number9
DOIs
Publication statusPublished - 1 Sept 2020
Externally publishedYes

Keywords

  • Acetaminophen
  • Graphite screen printed electrode
  • Nanopetal-structured MoWS
  • Tramadol

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