Generation of singlet oxygen and other radical species by quantum dot and carbon dot nanosensitizers

Roman Generalov*, Ingeborg L. Christensen, Wei Chen, Ya Ping Sun, Solveig Kristensen, Petras Juzenas

*Corresponding author for this work

Research output: Chapter in Book or Report/Conference proceedingConference Proceedingpeer-review

6 Citations (Scopus)

Abstract

Medicinal applications of luminescent semiconductor quantum dots are of growing interest. In spite of the fact that their fabrication and imaging applications have been extensively investigated for the last decade, very little is documented on photodynamic action of quantum dots. In this study we demonstrate generation of singlet oxygen and other radical species upon exposure of quantum dots to blue light and therapeutic red light. Extent of radical production can be readily modified by antioxidants. Lay and scientific communities are two sites concerning potential hazards and enthusiastic applications of nanotechnology. Synthesis of quantum dots composed of less toxic materials is of great interest. A new candidate is a ubiquitous element carbon, which on nanoscale exhibits strong photoluminescence.

Original languageEnglish
Title of host publication12th World Congress of the International Photodynamic Association - Photodynamic Therapy
Subtitle of host publicationBack to the Future
DOIs
Publication statusPublished - 2009
Externally publishedYes
Event12th World Congress of the International Photodynamic Association - Photodynamic Therapy: Back to the Future - Seattle, WA, United States
Duration: 11 Jun 200915 Jun 2009

Publication series

NameProgress in Biomedical Optics and Imaging - Proceedings of SPIE
Volume7380
ISSN (Print)1605-7422

Conference

Conference12th World Congress of the International Photodynamic Association - Photodynamic Therapy: Back to the Future
Country/TerritoryUnited States
CitySeattle, WA
Period11/06/0915/06/09

Keywords

  • Carbon dots
  • photodynamic therapy
  • photosensitization
  • quantum dots
  • radicals
  • singlet oxygen

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