TY - GEN
T1 - Acceleration of the acquisition of imaging probes using spatiotemporal processing
AU - Jin, Mingwu
AU - Zhao, Cong
AU - Yu, Jaehoon
AU - Chen, Wei
AU - Hao, Guiyang
AU - Sun, Xiankai
PY - 2013
Y1 - 2013
N2 - A quick localization of the tumor site to guide the therapeutic administration is important for an image guided cancer therapy to decrease both mortality and morbidity, especially in prolonged procedures, such as photodynamic and photothermal therapies. Consequently, the images have to be updated quickly enough to capture the patient motion and the movement of therapeutic device, which poses a significant challenge on functional imaging probes. Besides increasing the sensitivity of imaging detectors, advanced image processing methods may play an important role to overcome this challenge. In this work, we investigate the effectiveness of the spatiotemporal processing to shorten the acquisition time of each image frame to be able to capture the object motion with good image quality. The simulation study of beta imaging of a moving tumor phantom at different imaging dose levels demonstrates that the spatiotemporal processing can yield superior image quality compared to either a short acquisition or a prolonged acquisition with only spatial smoothing. The receiver operating characteristic curve analysis also reveals its advantage on the tumor detection, particularly at lower imaging dose or equivalently shorter acquisition time.
AB - A quick localization of the tumor site to guide the therapeutic administration is important for an image guided cancer therapy to decrease both mortality and morbidity, especially in prolonged procedures, such as photodynamic and photothermal therapies. Consequently, the images have to be updated quickly enough to capture the patient motion and the movement of therapeutic device, which poses a significant challenge on functional imaging probes. Besides increasing the sensitivity of imaging detectors, advanced image processing methods may play an important role to overcome this challenge. In this work, we investigate the effectiveness of the spatiotemporal processing to shorten the acquisition time of each image frame to be able to capture the object motion with good image quality. The simulation study of beta imaging of a moving tumor phantom at different imaging dose levels demonstrates that the spatiotemporal processing can yield superior image quality compared to either a short acquisition or a prolonged acquisition with only spatial smoothing. The receiver operating characteristic curve analysis also reveals its advantage on the tumor detection, particularly at lower imaging dose or equivalently shorter acquisition time.
UR - http://www.scopus.com/inward/record.url?scp=84904192215&partnerID=8YFLogxK
U2 - 10.1109/NSSMIC.2013.6829274
DO - 10.1109/NSSMIC.2013.6829274
M3 - Conference Proceeding
AN - SCOPUS:84904192215
SN - 9781479905348
T3 - IEEE Nuclear Science Symposium Conference Record
BT - 2013 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 2013 60th IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013
Y2 - 27 October 2013 through 2 November 2013
ER -