Acceleration of the acquisition of imaging probes using spatiotemporal processing

Mingwu Jin, Cong Zhao, Jaehoon Yu, Wei Chen, Guiyang Hao, Xiankai Sun

Research output: Chapter in Book or Report/Conference proceedingConference Proceedingpeer-review

4 Citations (Scopus)

Abstract

A quick localization of the tumor site to guide the therapeutic administration is important for an image guided cancer therapy to decrease both mortality and morbidity, especially in prolonged procedures, such as photodynamic and photothermal therapies. Consequently, the images have to be updated quickly enough to capture the patient motion and the movement of therapeutic device, which poses a significant challenge on functional imaging probes. Besides increasing the sensitivity of imaging detectors, advanced image processing methods may play an important role to overcome this challenge. In this work, we investigate the effectiveness of the spatiotemporal processing to shorten the acquisition time of each image frame to be able to capture the object motion with good image quality. The simulation study of beta imaging of a moving tumor phantom at different imaging dose levels demonstrates that the spatiotemporal processing can yield superior image quality compared to either a short acquisition or a prolonged acquisition with only spatial smoothing. The receiver operating characteristic curve analysis also reveals its advantage on the tumor detection, particularly at lower imaging dose or equivalently shorter acquisition time.

Original languageEnglish
Title of host publication2013 IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013
PublisherInstitute of Electrical and Electronics Engineers Inc.
ISBN (Print)9781479905348
DOIs
Publication statusPublished - 2013
Externally publishedYes
Event2013 60th IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013 - Seoul, Korea, Republic of
Duration: 27 Oct 20132 Nov 2013

Publication series

NameIEEE Nuclear Science Symposium Conference Record
ISSN (Print)1095-7863

Conference

Conference2013 60th IEEE Nuclear Science Symposium and Medical Imaging Conference, NSS/MIC 2013
Country/TerritoryKorea, Republic of
CitySeoul
Period27/10/132/11/13

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