A new type of cuprous-cysteamine sensitizers: Synthesis, optical properties and potential applications

Y. Wang, N. D. Alkhaldi, N. K. Pandey, L. Chudal, L. Y. Wang, L. W. Lin, M. B. Zhang*, Y. X. Yong, E. H. Amador, M. N. Huda*, W. Chen*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

18 Citations (Scopus)

Abstract

Herein, for the first time, we report a series of cuprous-cysteamine (Cu-Cy-X, X = F, Cl, Br, and I)) sensitizers that possess tunable fluorescence from orange to yellow. The Cu-Cy-X can generate reactive oxygen species (ROS), including singlet oxygen (1O2) in the order of Cu-Cy-I > Cu-Cy-Br > Cu-Cy-Cl ≈ Cu-Cy-F under UV and microwave excitation. Further study revealed that Cu-Cy-X has stability in the order of Cu-Cy-I > Cu-Cy-Br > Cu-Cy-Cl ≈ Cu-Cy-F. In this work, a detailed synthesis technique, crystal structure, optical properties, and mechanism of the observed trend in 1O2 generation, luminescence spectra, and anticancer effect are discussed in both theoretical and experimental points of view. These new materials will open a new door for photodynamic therapy and many other potential applications such as sensing, lighting, displays, labeling, and medical imaging.

Original languageEnglish
Article number100435
JournalMaterials Today Physics
Volume19
DOIs
Publication statusPublished - Jul 2021
Externally publishedYes

Keywords

  • Cuprous-cysteamine
  • Density functional theory (DFT)
  • Luminescence
  • Microwave
  • Photodynamic therapy
  • Reactive oxygen species
  • Sensitizer
  • Singlet oxygen

Fingerprint

Dive into the research topics of 'A new type of cuprous-cysteamine sensitizers: Synthesis, optical properties and potential applications'. Together they form a unique fingerprint.

Cite this