Projects per year
Personal profile
Personal profile
Dr. Kozo Hamada is an Associate Professor at the Department of Biological Sciences in the School of Science. He serves as the Principal Investigator (PI) leading his laboratory at Xian Jiaotong Liverpool University (XJTLU). He obtained his Ph.D. degree by the study of neurotransmitter serotonin and catecholamines at the University of Tokyo (Department of Biomedical Chemistry, Supervisor: Prof. Katsuji Takai). Over the past 20 years, he has dedicated his efforts to studying signal transductions, calcium signaling, and the structural biology of receptors and channels at institutions such as the University of Tokyo and RIKEN in Japan. His scientific interests encompass chemical signaling and related diseases, and he will focus on the development of new biomedical maneuvers to address human diseases, including neurodegenerative diseases and cancer.Dr. Hamada actively encourages students and collaborators to engage in his projects. For inquiries, you can reach him via email at Kozo.Hamada@xjtlu.edu.cn.
Research interests
Protein Engineering
Signal Transduction
Protein Biogenesis
Neurodegenerative Disease
Protein Plasticity
Brain Biochemistry
Protein Crystallography
Calcium Signaling
Experience
2023-Present Associate Professor, XJTLU, China
2019-2023 Research Associate Professor, ShanghaiTech University, China
2019-Present Visiting researcher, Faculty of Science, Toho University, Japan
2018-2022 Researcher, Faculty of Pharmacy, Kindai Unversity, Japan
2010-2018 Research Scientist, Brain Science Institute, RIKEN, Japan
2003-2010 Researcher, Japan Science and Technology Agency, Japan
1998-2003 Research Scientist, Brain Science Institute, RIKEN, Japan
Teaching
BIO105 Chemical Principles of Life
BIO113 Molecular Biology Techniques
BIO303 Final Year Project
Related documents
Education/Academic qualification
Ph. D. Department of Biomedical Chemistry, Institute of International Health, The University of Tokyo -1998
M. Sc. Department of Biochemistry and Nutrition, School of Health Science, The University of Tokyo -1993
B. Sc. Department of Biochemistry and Nutrition, School of Health Science, The University of Tokyo -1991
Person Types
- Staff
Fingerprint
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Collaborations and top research areas from the last five years
Projects
- 2 Not started
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The mechanism of ammonia accumulation promotes liver cancer progression via calcium channel-mTORC2-SREBP1-lipogenesis dependent manner
Dai, W., Wang, S., Chen, G., Elkord, E., Hamada, K., Cheng, K., Xu, J., Huang, S., Yang, C., Ma, J. & Bin, U.
1/01/25 → 31/12/28
Project: Governmental Research Project
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NSFC General Program: The mechanism of ammonia accumulation promotes liver cancer progression via calcium channel-mTORC2-SREBP1-lipogenesis dependent manner
Dai, W., Hamada, K., Elkord, E. & Cheng, K.
1/01/25 → 31/12/28
Project: Governmental Research Project
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A non-canonical role for pyruvate kinase M2 as a functional modulator of Ca2+ signalling through IP3 receptors
Lavik, A. R., McColl, K. S., Lemos, F. O., Kerkhofs, M., Zhong, F., Harr, M., Schlatzer, D., Hamada, K., Mikoshiba, K., Crea, F., Bultynck, G., Bootman, M. D., Parys, J. B. & Distelhorst, C. W., Apr 2022, In: Biochimica et Biophysica Acta - Molecular Cell Research. 1869, 4, 119206.Research output: Contribution to journal › Article › peer-review
Open Access9 Citations (Scopus) -
Bcl-xL acts as an inhibitor of IP3R channels, thereby antagonizing Ca2+-driven apoptosis
Rosa, N., Ivanova, H., Wagner, L. E., Kale, J., La Rovere, R., Welkenhuyzen, K., Louros, N., Karamanou, S., Shabardina, V., Lemmens, I., Vandermarliere, E., Hamada, K., Ando, H., Rousseau, F., Schymkowitz, J., Tavernier, J., Mikoshiba, K., Economou, A., Andrews, D. W., Parys, J. B., & 2 others , Apr 2022, In: Cell Death and Differentiation. 29, 4, p. 788-805 18 p.Research output: Contribution to journal › Article › peer-review
Open Access51 Citations (Scopus) -
Sequestration of the PKC ortholog Pck2 in stress granules as a feedback mechanism of MAPK signaling in fission yeast
Kanda, Y., Satoh, R., Takasaki, T., Tomimoto, N., Tsuchiya, K., Tsai, C. A., Tanaka, T., Kyomoto, S., Hamada, K., Fujiwara, T. & Sugiura, R., Jan 2021, In: Journal of Cell Science. 134, 2, jcs250191.Research output: Contribution to journal › Article › peer-review
Open Access13 Citations (Scopus) -
IP3 Receptor Plasticity Underlying Diverse Functions
Hamada, K. & Mikoshiba, K., 2020, In: Annual Review of Physiology. 82, p. 151-176 26 p.Research output: Contribution to journal › Review article › peer-review
Open Access36 Citations (Scopus) -
Type 3 Inositol 1,4,5-Trisphosphate Receptor is a Crucial Regulator of Calcium Dynamics Mediated by Endoplasmic Reticulum in HEK Cells
Yue, L., Wang, L., Du, Y., Zhang, W., Hamada, K., Matsumoto, Y., Jin, X., Zhou, Y., Mikoshiba, K., Gill, D. L., Han, S. & Wang, Y., 22 Jan 2020, In: Cells. 9, 2, 2138.Research output: Contribution to journal › Article › peer-review
Open Access14 Citations (Scopus)