Synthesis of bioactive 1-alkyl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent

Qian Zhang; Jaya P. Shrestha; Cheng Wei Tom Chang

doi:10.1016/j.tetlet.2014.01.129

Synthesis of bioactive 1-alkyl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent

Qian Zhang, Jaya P. Shrestha, Cheng Wei Tom Chang^*

^*Corresponding author for this work

Utah State University

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

Through a [2+3] cycloaddition reaction, a new environmentally friendly method was developed to enable the synthesis of bioactive 1-alkyl-1H-naphtho[2, 3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent with good yields and minimum requirement of purification. This new green synthetic protocol is simple and suitable for scale-up synthesis.

Original language	English
Pages (from-to)	1839-1842
Number of pages	4
Journal	Tetrahedron Letters
Volume	55
Issue number	10
DOIs	https://doi.org/10.1016/j.tetlet.2014.01.129
Publication status	Published - 5 Mar 2014
Externally published	Yes

Keywords

Bioactive
Green chemistry
Indanedione
Naphthoquinone
Water as solvent

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10.1016/j.tetlet.2014.01.129

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title = "Synthesis of bioactive 1-alkyl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent",

abstract = "Through a [2+3] cycloaddition reaction, a new environmentally friendly method was developed to enable the synthesis of bioactive 1-alkyl-1H-naphtho[2, 3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent with good yields and minimum requirement of purification. This new green synthetic protocol is simple and suitable for scale-up synthesis.",

keywords = "Bioactive, Green chemistry, Indanedione, Naphthoquinone, Water as solvent",

author = "Qian Zhang and Shrestha, {Jaya P.} and Chang, {Cheng Wei Tom}",

note = "Funding Information: We acknowledge the support from the Department of Chemistry and Biochemistry, Utah State University. ",

year = "2014",

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doi = "10.1016/j.tetlet.2014.01.129",

language = "English",

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journal = "Tetrahedron Letters",

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T1 - Synthesis of bioactive 1-alkyl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent

AU - Zhang, Qian

AU - Shrestha, Jaya P.

AU - Chang, Cheng Wei Tom

N1 - Funding Information: We acknowledge the support from the Department of Chemistry and Biochemistry, Utah State University.

PY - 2014/3/5

Y1 - 2014/3/5

N2 - Through a [2+3] cycloaddition reaction, a new environmentally friendly method was developed to enable the synthesis of bioactive 1-alkyl-1H-naphtho[2, 3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent with good yields and minimum requirement of purification. This new green synthetic protocol is simple and suitable for scale-up synthesis.

AB - Through a [2+3] cycloaddition reaction, a new environmentally friendly method was developed to enable the synthesis of bioactive 1-alkyl-1H-naphtho[2, 3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent with good yields and minimum requirement of purification. This new green synthetic protocol is simple and suitable for scale-up synthesis.

KW - Bioactive

KW - Green chemistry

KW - Indanedione

KW - Naphthoquinone

KW - Water as solvent

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U2 - 10.1016/j.tetlet.2014.01.129

DO - 10.1016/j.tetlet.2014.01.129

M3 - Article

AN - SCOPUS:84896710012

SN - 0040-4039

VL - 55

SP - 1839

EP - 1842

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 10

ER -

Synthesis of bioactive 1-alkyl-1H-naphtho[2,3-d][1,2,3]triazole-4,9-diones and N-aryl-2-aminomethylene-1,3-indanediones using water as the solvent

Abstract

Keywords

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