Signal properties of brain gangliosides

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Abstract

There are some data on gangliosides - sialoacid-containing complex glycolipids - showing that gangliosides due to their physico-chemical properties and specific distribution are able to serve as specific signal molecules in different, evolutionary distant organisms. Individual gangliosides are widespread in the CNS, demonstrating variety of signalling mechanisms. These mechanisms have different degree of molecular complexity and are likely to be the object of natural evolution of gangliosides signal properties. The review summarizes data on possible signal properties of gangliosides in terms of their complication and supposed evolution of mechanisms.

Original languageEnglish
Pages (from-to)15-19
Number of pages5
JournalUkrain'skyi Biokhimichnyi Zhurnal
Volume68
Issue number2
Publication statusPublished - 1996
Externally publishedYes

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