TY - GEN
T1 - Predict two-dimensional protein folding based on hydrophobic-polar lattice model and chaotic clonal genetic algorithm
AU - Wang, Shuihua
AU - Wu, Lenan
AU - Huo, Yuankai
AU - Wu, Xueyan
AU - Wang, Hainan
AU - Zhang, Yudong
N1 - Publisher Copyright:
© Springer International Publishing AG 2016.
PY - 2016
Y1 - 2016
N2 - In order to improve the performance of prediction of protein folding problem, we introduce a relatively new chaotic clonal genetic algorithm (abbreviated as CCGA) to solve the 2D hydrophobic-polar lattice model. Our algorithm combines three successful components—(i) standard genetic algorithm (SGA), (ii) clonal selection algorithm (CSA), and (iii) chaotic operator. We compared this proposed CCGA with SGA, artificial immune system (AIS), and immune genetic algorithm (IGA) for various chain lengths. It demonstrated that CCGA had better performance than other methods over large-sized protein chains.
AB - In order to improve the performance of prediction of protein folding problem, we introduce a relatively new chaotic clonal genetic algorithm (abbreviated as CCGA) to solve the 2D hydrophobic-polar lattice model. Our algorithm combines three successful components—(i) standard genetic algorithm (SGA), (ii) clonal selection algorithm (CSA), and (iii) chaotic operator. We compared this proposed CCGA with SGA, artificial immune system (AIS), and immune genetic algorithm (IGA) for various chain lengths. It demonstrated that CCGA had better performance than other methods over large-sized protein chains.
KW - Artificial immune system
KW - Chaotic clonal genetic algorithm
KW - Clonal selection algorithm
KW - Hydrophobic-polar model
KW - Protein folding
UR - http://www.scopus.com/inward/record.url?scp=84989869202&partnerID=8YFLogxK
U2 - 10.1007/978-3-319-46257-8_2
DO - 10.1007/978-3-319-46257-8_2
M3 - Conference Proceeding
AN - SCOPUS:84989869202
SN - 9783319462561
T3 - Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics)
SP - 10
EP - 17
BT - Intelligent Data Engineering and Automated Learning - 17th International Conference, IDEAL 2016, Proceedings
A2 - Zhang, Daoqiang
A2 - Gao, Yang
A2 - Yin, Hujun
A2 - Li, Bin
A2 - Li, Yun
A2 - Yang, Ming
A2 - Klawonn, Frank
A2 - Tallón-Ballesteros, Antonio J.
PB - Springer Verlag
T2 - 17th International Conference on Intelligent Data Engineering and Automated Learning, IDEAL 2016
Y2 - 12 October 2016 through 14 October 2016
ER -