Abstract
Zebrafish (Danio rerio) share high genetic and physiological similarity with mammals and possess complex phenotypes in all major, evolutionarily conserved, neurobehavioral domains. Zebrafish are also rapidly emerging as a promising novel model organism in neuroimmunology and psychoneuroimmunology research. Here, we summarize neuroimmune mechanisms and their experimental modulation in zebrafish, and discuss some other relevant physiological aspects, such as the gut microbiota-brain interplay, as well as the translational insights from zebrafish neuroimmune models.
Original language | English |
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Title of host publication | Translational Neuroimmunology |
Subtitle of host publication | Neuroinflammation: Volume 7 |
Publisher | Elsevier |
Pages | 37-45 |
Number of pages | 9 |
Volume | 7 |
ISBN (Electronic) | 9780323858410 |
ISBN (Print) | 9780323900713 |
DOIs | |
Publication status | Published - 1 Jan 2023 |
Externally published | Yes |
Keywords
- Behavior
- Genetic models
- Gut microbiota
- Stress
- The immune system
- Zebrafish