Multiply-charged negative clusters of adenosine-5′-monophosphate in the gas phase

Bo Liu*, Preben Hvelplund, Steen Brøndsted Nielsen

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

6 Citations (Scopus)

Abstract

Multiply-charged noncovalent cluster anions of adenosine-5′- monophosphate (AMP) were formed by electrospray ionization (ESI). Ions in higher charge states were observed when the ions were accumulated in an ion trap with helium buffer gas before detection. We determined the smallest size (n a) or appearance size as a function of charge state (q), i.e., n a = 4 for q = 2, na = 8 for q = 3, and na = 13 for q = 4. The relation between na and q can be described by a charged droplet model. When the size is larger than na for a given q, the fragmentation pathway of an anion cluster is dominated by loss of neutral fragments. In contrast, when the size approaches the appearance size, only charged fragments are formed.

Original languageEnglish
Pages (from-to)1840-1845
Number of pages6
JournalJournal of the American Society for Mass Spectrometry
Volume16
Issue number11
DOIs
Publication statusPublished - Nov 2005
Externally publishedYes

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