IR-spectral signatures of aromatic-sugar complexes: Probing carbohydrate-protein interactions

James Screen*, E. Cristina Stanca-Kaposta, David P. Gamblin, Bo Liu, Neil A. Macleod, Lavina C. Snoek, Benjamin G. Davis, John P. Simons

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

92 Citations (Scopus)

Abstract

(Figure Presented) Key interactions: Sugar-arene complexes have been created in molecular-beam experiments and observed by IR ion-dip spectroscopy in the gas phase. These complexes are powerful models of the selective recognition seen in protein-sugar complexes, for example between the galactose-specific lectin from Artocarpus hirsute and MeGal (see picture).

Original languageEnglish
Pages (from-to)3644-3648
Number of pages5
JournalAngewandte Chemie - International Edition
Volume46
Issue number20
DOIs
Publication statusPublished - 2007
Externally publishedYes

Keywords

  • Carbohydrates
  • Density functional calculations
  • Molecular recognition
  • Vibrational spectroscopy

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