Identification and stereochemistry of the product of 4-HPPD catalyzed oxidation of the ketoacid of methionine

Robert M. Adlington; Jack E. Baldwin; Nicholas P. Crouch; Meng Huee Lee; Colin H. MacKinnon

doi:10.1016/0960-894X(96)00362-9

Identification and stereochemistry of the product of 4-HPPD catalyzed oxidation of the ketoacid of methionine

Robert M. Adlington, Jack E. Baldwin, Nicholas P. Crouch^*, Meng Huee Lee, Colin H. MacKinnon

^*Corresponding author for this work

University of Oxford

Research output: Contribution to journal › Article › peer-review

9 Citations (Scopus)

Abstract

4-Hydroxyphenylpyruvate dioxygenase catalyzes the conversion of 2-oxo-5-thiahexanoic acid 1, the ketoacid from methionine to an unequal mixture of 4-thiapentanoic acid-4-oxide enantiomers 2a.

Original language	English
Pages (from-to)	2003-2006
Number of pages	4
Journal	Bioorganic and Medicinal Chemistry Letters
Volume	6
Issue number	16
DOIs	https://doi.org/10.1016/0960-894X(96)00362-9
Publication status	Published - 20 Aug 1996
Externally published	Yes

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title = "Identification and stereochemistry of the product of 4-HPPD catalyzed oxidation of the ketoacid of methionine",

abstract = "4-Hydroxyphenylpyruvate dioxygenase catalyzes the conversion of 2-oxo-5-thiahexanoic acid 1, the ketoacid from methionine to an unequal mixture of 4-thiapentanoic acid-4-oxide enantiomers 2a.",

author = "Adlington, {Robert M.} and Baldwin, {Jack E.} and Crouch, {Nicholas P.} and Lee, {Meng Huee} and MacKinnon, {Colin H.}",

year = "1996",

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journal = "Bioorganic and Medicinal Chemistry Letters",

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T1 - Identification and stereochemistry of the product of 4-HPPD catalyzed oxidation of the ketoacid of methionine

AU - Adlington, Robert M.

AU - Baldwin, Jack E.

AU - Crouch, Nicholas P.

AU - Lee, Meng Huee

AU - MacKinnon, Colin H.

PY - 1996/8/20

Y1 - 1996/8/20

N2 - 4-Hydroxyphenylpyruvate dioxygenase catalyzes the conversion of 2-oxo-5-thiahexanoic acid 1, the ketoacid from methionine to an unequal mixture of 4-thiapentanoic acid-4-oxide enantiomers 2a.

AB - 4-Hydroxyphenylpyruvate dioxygenase catalyzes the conversion of 2-oxo-5-thiahexanoic acid 1, the ketoacid from methionine to an unequal mixture of 4-thiapentanoic acid-4-oxide enantiomers 2a.

UR - http://www.scopus.com/inward/record.url?scp=0030594980&partnerID=8YFLogxK

U2 - 10.1016/0960-894X(96)00362-9

DO - 10.1016/0960-894X(96)00362-9

M3 - Article

AN - SCOPUS:0030594980

SN - 0960-894X

VL - 6

SP - 2003

EP - 2006

JO - Bioorganic and Medicinal Chemistry Letters

JF - Bioorganic and Medicinal Chemistry Letters

IS - 16

ER -

Identification and stereochemistry of the product of 4-HPPD catalyzed oxidation of the ketoacid of methionine

Abstract

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