TY - JOUR
T1 - Formation and stability of charged amino acid clusters and the role of chirality
AU - Concina, B.
AU - Hvelplund, P.
AU - Nielsen, A. B.
AU - Nielsen, S. Brøndsted
AU - Rangama, J.
AU - Liu, B.
AU - Tomita, S.
PY - 2006/2
Y1 - 2006/2
N2 - Amino acid clusters have been studied by several groups and most notably magic number clusters and chiral recognition have been reported. In this work, we have studied the formation of amino acid clusters by electrospray ionization (ESI) and their stability by high-energy collision-induced dissociation (CID). Appearance sizes were determined for multiply charged clusters where the charge is either due to protons or to sodium ions. Finally, we conclude that chiral selectivity plays an important role in cluster formation but seems to be of minor importance for the fragmentation of mixed clusters.
AB - Amino acid clusters have been studied by several groups and most notably magic number clusters and chiral recognition have been reported. In this work, we have studied the formation of amino acid clusters by electrospray ionization (ESI) and their stability by high-energy collision-induced dissociation (CID). Appearance sizes were determined for multiply charged clusters where the charge is either due to protons or to sodium ions. Finally, we conclude that chiral selectivity plays an important role in cluster formation but seems to be of minor importance for the fragmentation of mixed clusters.
UR - http://www.scopus.com/inward/record.url?scp=31844443079&partnerID=8YFLogxK
U2 - 10.1016/j.jasms.2005.10.014
DO - 10.1016/j.jasms.2005.10.014
M3 - Article
C2 - 16434210
AN - SCOPUS:31844443079
SN - 1044-0305
VL - 17
SP - 275
EP - 279
JO - Journal of the American Society for Mass Spectrometry
JF - Journal of the American Society for Mass Spectrometry
IS - 2
ER -