Abstract
Individual classes of nanoparticles have made a tremendous impact on the biomedical sciences, with advances in imaging, single-molecule tracking, and cellular mechanotransduction. However, the future of nanotechnology will probably depend on the combination of attributes from several different nanomaterials. Here, one class of hybrid nanoparticles that possess both fluorescent and magnetic functionalities is described. These nanocomposites are created by combining fluorescent nanoparticles with magnetic iron oxide nanoparticles in an encapsulating micelle or solid polymer sphere. The resulting composites range from 10 to 500 nm in size and display both fluorescent and magnetic properties of the constituent nano-particles. These particles are demonstrated as in vitro cellular labels, a precursor to future in vivo studies; they will expand in vivo imaging options by providing the capability for both magnetic resonance (MR) and fluorescence imaging.
| Original language | English |
|---|---|
| Pages (from-to) | 81-86 |
| Number of pages | 6 |
| Journal | Proceedings of the Institution of Mechanical Engineers, Part N: Journal of Nanoengineering and Nanosystems |
| Volume | 223 |
| Issue number | 3 |
| DOIs | |
| Publication status | Published - 1 Jan 2010 |
| Externally published | Yes |
Keywords
- carbon nanoparticles
- iron oxide nanoparticles
- multimodal imaging
- quantum dots