Flexible synthesis of polyfunctionalised 3-fluoropyrroles

Thomas J. Cogswell; Craig S. Donald; Rodolfo Marquez

doi:10.1039/c5ob02155c

Flexible synthesis of polyfunctionalised 3-fluoropyrroles

Thomas J. Cogswell, Craig S. Donald, Rodolfo Marquez^*

^*Corresponding author for this work

Department of Chemistry and Materials Science

Research output: Contribution to journal › Article › peer-review

15 Citations (Scopus)

Abstract

An efficient and selective approach for the synthesis of polyfunctionalised 3-fluoropyrroles has been developed starting from commercial aldehydes. The methodology is concise, efficient and allows for the modular and systematic assembly of polysubstituted 3-fluoropyrroles. This synthesis provides an alternative and highly convergent strategy for the generation of these chemically and biologically important units.

Original language	English
Pages (from-to)	183-190
Number of pages	8
Journal	Organic and Biomolecular Chemistry
Volume	14
Issue number	1
DOIs	https://doi.org/10.1039/c5ob02155c
Publication status	Published - 2015

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title = "Flexible synthesis of polyfunctionalised 3-fluoropyrroles",

abstract = "An efficient and selective approach for the synthesis of polyfunctionalised 3-fluoropyrroles has been developed starting from commercial aldehydes. The methodology is concise, efficient and allows for the modular and systematic assembly of polysubstituted 3-fluoropyrroles. This synthesis provides an alternative and highly convergent strategy for the generation of these chemically and biologically important units.",

author = "Cogswell, {Thomas J.} and Donald, {Craig S.} and Rodolfo Marquez",

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AU - Cogswell, Thomas J.

AU - Donald, Craig S.

AU - Marquez, Rodolfo

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Y1 - 2015

N2 - An efficient and selective approach for the synthesis of polyfunctionalised 3-fluoropyrroles has been developed starting from commercial aldehydes. The methodology is concise, efficient and allows for the modular and systematic assembly of polysubstituted 3-fluoropyrroles. This synthesis provides an alternative and highly convergent strategy for the generation of these chemically and biologically important units.

AB - An efficient and selective approach for the synthesis of polyfunctionalised 3-fluoropyrroles has been developed starting from commercial aldehydes. The methodology is concise, efficient and allows for the modular and systematic assembly of polysubstituted 3-fluoropyrroles. This synthesis provides an alternative and highly convergent strategy for the generation of these chemically and biologically important units.

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U2 - 10.1039/c5ob02155c

DO - 10.1039/c5ob02155c

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AN - SCOPUS:84951292161

SN - 1477-0520

VL - 14

SP - 183

EP - 190

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 1

ER -

Flexible synthesis of polyfunctionalised 3-fluoropyrroles

Abstract

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