Experimental models in serotonin transporter research

Allan V. Kalueff, Justin L. Laporte

Research output: Book/Report/Edited volumeBookpeer-review

Abstract

The serotonin transporter is a key brain protein that modulates the reuptake of the neurotransmitter serotonin from synaptic spaces back into the presynaptic neuron. This control over neuronal signalling makes it a prime area of neuroscientific study. In this book an international team of top experts introduce and explicate the role of serotonin and the serotonin transporter in both human and animal brains. They demonstrate the relevance of the transporter and indeed the serotonergic system to substrates of neuropsychiatric disorders, and explain how this knowledge is translated into valid animal models that will help foster new discoveries in human neurobiology. Writing for graduate students and academic researchers, they provide a comprehensive coverage of a wide spectrum of data from animal experimentation to clinical psychiatry, creating the only book exclusively dedicated to this exciting new avenue of brain research.

Original languageEnglish
PublisherCambridge University Press
Number of pages367
ISBN (Electronic)9780511729935
ISBN (Print)9780521514873
DOIs
Publication statusPublished - 1 Jan 2010
Externally publishedYes

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