Enhancement of biophoton emission of prostate cancer cells by Ag nanoparticles

Marius Hossu; Lun Ma; Xiaoju Zou; Wei Chen

doi:10.1007/s12645-013-0034-7

Enhancement of biophoton emission of prostate cancer cells by Ag nanoparticles

Marius Hossu, Lun Ma, Xiaoju Zou, Wei Chen^*

^*Corresponding author for this work

University of Texas at Arlington

Research output: Contribution to journal › Article › peer-review

29 Citations (Scopus)

Abstract

Ultraweak intrinsic bioluminescence of cancer cell is a noninvasive method of assessing bioenergetic status of the investigated cells. This weak biophoton emission generated by prostate cancer cells (PC₃) was measured in the presence of Ag nanoparticles and its correlation with singlet oxygen production was investigated. The comparison between nanoparticles concentration, bioluminescence intensity, and cell survival showed that Ag nanoparticles do not significantly affect cell survival at used concentration but they increase cell bioluminescent processes. It was also confirmed that singlet oxygen contributes to biophoton emission, that Ag nanoparticles increase this contribution, and that there are secondary mechanisms independent of singlet oxygen by which Ag nanoparticles contribute to increased cellular bioluminescence, possibly through plasmon resonance enhancement of intrinsic fluorescence.

Original language	English
Pages (from-to)	21-26
Number of pages	6
Journal	Cancer Nanotechnology
Volume	4
Issue number	1-3
DOIs	https://doi.org/10.1007/s12645-013-0034-7
Publication status	Published - Jun 2013
Externally published	Yes

Keywords

Bioluminescence
Biophoton
Cancer
PC3
Plasmon resonance
Silver nanoparticle
Singlet oxygen

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.1007/s12645-013-0034-7

Cite this

@article{2dfbd9ec6b944a30b2b039f0d09a14d8,

title = "Enhancement of biophoton emission of prostate cancer cells by Ag nanoparticles",

abstract = "Ultraweak intrinsic bioluminescence of cancer cell is a noninvasive method of assessing bioenergetic status of the investigated cells. This weak biophoton emission generated by prostate cancer cells (PC3) was measured in the presence of Ag nanoparticles and its correlation with singlet oxygen production was investigated. The comparison between nanoparticles concentration, bioluminescence intensity, and cell survival showed that Ag nanoparticles do not significantly affect cell survival at used concentration but they increase cell bioluminescent processes. It was also confirmed that singlet oxygen contributes to biophoton emission, that Ag nanoparticles increase this contribution, and that there are secondary mechanisms independent of singlet oxygen by which Ag nanoparticles contribute to increased cellular bioluminescence, possibly through plasmon resonance enhancement of intrinsic fluorescence.",

keywords = "Bioluminescence, Biophoton, Cancer, PC3, Plasmon resonance, Silver nanoparticle, Singlet oxygen",

author = "Marius Hossu and Lun Ma and Xiaoju Zou and Wei Chen",

year = "2013",

month = jun,

doi = "10.1007/s12645-013-0034-7",

language = "English",

volume = "4",

pages = "21--26",

journal = "Cancer Nanotechnology",

issn = "1868-6958",

number = "1-3",

}

TY - JOUR

T1 - Enhancement of biophoton emission of prostate cancer cells by Ag nanoparticles

AU - Hossu, Marius

AU - Ma, Lun

AU - Zou, Xiaoju

AU - Chen, Wei

PY - 2013/6

Y1 - 2013/6

N2 - Ultraweak intrinsic bioluminescence of cancer cell is a noninvasive method of assessing bioenergetic status of the investigated cells. This weak biophoton emission generated by prostate cancer cells (PC3) was measured in the presence of Ag nanoparticles and its correlation with singlet oxygen production was investigated. The comparison between nanoparticles concentration, bioluminescence intensity, and cell survival showed that Ag nanoparticles do not significantly affect cell survival at used concentration but they increase cell bioluminescent processes. It was also confirmed that singlet oxygen contributes to biophoton emission, that Ag nanoparticles increase this contribution, and that there are secondary mechanisms independent of singlet oxygen by which Ag nanoparticles contribute to increased cellular bioluminescence, possibly through plasmon resonance enhancement of intrinsic fluorescence.

AB - Ultraweak intrinsic bioluminescence of cancer cell is a noninvasive method of assessing bioenergetic status of the investigated cells. This weak biophoton emission generated by prostate cancer cells (PC3) was measured in the presence of Ag nanoparticles and its correlation with singlet oxygen production was investigated. The comparison between nanoparticles concentration, bioluminescence intensity, and cell survival showed that Ag nanoparticles do not significantly affect cell survival at used concentration but they increase cell bioluminescent processes. It was also confirmed that singlet oxygen contributes to biophoton emission, that Ag nanoparticles increase this contribution, and that there are secondary mechanisms independent of singlet oxygen by which Ag nanoparticles contribute to increased cellular bioluminescence, possibly through plasmon resonance enhancement of intrinsic fluorescence.

KW - Bioluminescence

KW - Biophoton

KW - Cancer

KW - PC3

KW - Plasmon resonance

KW - Silver nanoparticle

KW - Singlet oxygen

UR - http://www.scopus.com/inward/record.url?scp=84878910680&partnerID=8YFLogxK

U2 - 10.1007/s12645-013-0034-7

DO - 10.1007/s12645-013-0034-7

M3 - Article

AN - SCOPUS:84878910680

SN - 1868-6958

VL - 4

SP - 21

EP - 26

JO - Cancer Nanotechnology

JF - Cancer Nanotechnology

IS - 1-3

ER -

Enhancement of biophoton emission of prostate cancer cells by Ag nanoparticles

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this