DNA aptasensor based electrochemiluminescence device for visualized detection of trace arsenite in high-salinity water samples

Background: Current available detection methods can not afford the direct and precise detection of trace arsenite (As(III)) in high-salinity water bodies. Therefore, the development of device with low limit of detection (LOD) for the early detection of As(III) in high-salinity water samples is of vital importance to secure environment and food safety. Results: Herein, we report a rapid and visualized device for trace As(III) determination in practical water samples by DNA aptasensor based electrochemiluminescence (ECL) method. Specifically, we firstly prepare polymer dots by nanoprecipitation method, followed by surface modification of specific DNA aptamer of As(III). The Pdots can be applied on electrodes to give detection device for trace As(III) detection with a low LOD at 0.24 ng/L with robust selectivity. More importantly, the device can be used for the effective visualized determination of As(III) in practical high-salinity water samples. Significance: This device can be applied to detect visualized detection of trace arsenite in high-salinity water samples, which holds a pivotal role in the realms of environment and food safety research.