TY - GEN
T1 - Database Construction and AI Design of Bioink for 3D Bio-printing
AU - Xue, Xuan
N1 - Dr. Xuan Xue is currently an Assistant Professor in the Department of Chemistry at Xi'an Jiaotong-Liverpool University, Suzhou, China. She received her Ph.D. degree from the University of Nottingham (UK) with full Oversea Research Scholarship. After her Ph.D., she has achieved valuable experience in both academia and industry R&D. Her research interests cover a wide range of interdisciplinary research areas from materials science, polymer chemistry, surface chemistry, 3D-bioprinting to tissue engineering, cell biology and microbiology. Currently, she is working closely with collaborators from virology and immunology on the discovery of polymer materials using high throughput screening methodology, and the development of novel protective materials. In addition, she is involved in the National Key Research and Development Program led by Prof. Yuwen Cui (Nanjing Tech University, Scientific Head of AI Materials Design Platform), focusing on the AI design of 3D bio-printed organoids-on-chip project. Both projects are now open for fully-funded PhD students to join.
PY - 2023/7
Y1 - 2023/7
N2 - The similarities of organoids to actual organs make them more attractive for target identification and validation early in the pipeline, whereas organs-on-a-chip as more-reproducible and more-controllable engineered constructs are better suited for efficacy and safety screening. Generally, the National Key Research and Development Program (NKRDP) Project is to combine the multidisciplinary advances of experimental (biomaterials and 3D bio-printing, microfluidic chip and organoids) and computational (machine learning and simulation) technologies to provide theoretical support for cancer research progressing and organoids-on-chip products for reliable and cost-effective drug discovery. Dr Xue’s project belongs to the Work Packages IV of the NKRDP, the aims of which are 1) to investigate smart bioink materials for construction of tumor organoids by 3D bioprinting, and the structure-function interlink between the microscopic and macroscopic properties and 3D printability; and 2) to develop multi-fidelity database and machine learning model for 3D bioprinting and organoids-on-chip design. In this talk, she will give a brief overview of the research background, the current progress and the conclusion of the research output so far, and an outline of the future work plan.
AB - The similarities of organoids to actual organs make them more attractive for target identification and validation early in the pipeline, whereas organs-on-a-chip as more-reproducible and more-controllable engineered constructs are better suited for efficacy and safety screening. Generally, the National Key Research and Development Program (NKRDP) Project is to combine the multidisciplinary advances of experimental (biomaterials and 3D bio-printing, microfluidic chip and organoids) and computational (machine learning and simulation) technologies to provide theoretical support for cancer research progressing and organoids-on-chip products for reliable and cost-effective drug discovery. Dr Xue’s project belongs to the Work Packages IV of the NKRDP, the aims of which are 1) to investigate smart bioink materials for construction of tumor organoids by 3D bioprinting, and the structure-function interlink between the microscopic and macroscopic properties and 3D printability; and 2) to develop multi-fidelity database and machine learning model for 3D bioprinting and organoids-on-chip design. In this talk, she will give a brief overview of the research background, the current progress and the conclusion of the research output so far, and an outline of the future work plan.
M3 - Conference Proceeding
BT - 2023 International Workshop on Materials and Al-based Design
T2 - 2023 International Workshop on Materials and Al-based Design
Y2 - 5 July 2023
ER -