Abstract
The paper reviews the role of GABA-ergic mechanisms in anxiety and summarizes the data on complex bimodal effects produced by GABA-ergic agents on receptors and behavioral measures of anxiety. Possible physiological mechanisms of such effects on anxiety have been discussed. The paper reviews some paradoxical anxiotropic effects produced by certain GABA-ergic agents in behavioral tests of anxiety. Currently existing traditional views on GABA-ergic mechanisms that underlie anxiety and anxiety-related states are critically re-considered.
| Original language | English |
|---|---|
| Pages (from-to) | 208-213 |
| Number of pages | 6 |
| Journal | Neurophysiology |
| Volume | 28 |
| Issue number | 6 |
| DOIs | |
| Publication status | Published - 1996 |
| Externally published | Yes |