Assessment of general locomotor activity and anxiety in zebrafish (Danio rerio) in the light-dark box (tank), the shoaling test, in the novel tank and the open field tests

David S. Galstyan; Tatyana O. Kolesnikova; Yurii M. Kositsyn; Konstantin N. Zabegalov; Mariya A. Gubaidullina; Gleb O. Maslov; Konstantin A. Demin; Allan V. Kalueff

doi:10.17816/RCF202123-133

Assessment of general locomotor activity and anxiety in zebrafish (Danio rerio) in the light-dark box (tank), the shoaling test, in the novel tank and the open field tests

David S. Galstyan, Tatyana O. Kolesnikova, Yurii M. Kositsyn, Konstantin N. Zabegalov, Mariya A. Gubaidullina, Gleb O. Maslov, Konstantin A. Demin, Allan V. Kalueff^*

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

1 Citation (Scopus)

Abstract

Anxiety is a complex and multifaceted neurobehavioral disorder that includes various forms of chronic pathological anxiety and fears, and is also the cause for various comorbid pathologies, such as depression or cardiovascular diseases. Behavioral testing of various model organisms, including the zebrafish (Danio rerio), is widely used to study neurobiological mechanisms of anxiety. Here, we discuss the novel tank test, the open field test, light-dark box and shoaling test that are widely used in translational biological psychiatry to characterize anxiety-related behavioral phenotypes in zebrafish.

Original language	English
Pages (from-to)	123-133
Number of pages	11
Journal	Reviews on Clinical Pharmacology and Drug Therapy
Volume	20
Issue number	2
DOIs	https://doi.org/10.17816/RCF202123-133
Publication status	Published - 2022
Externally published	Yes

Keywords

anxiety
Danio rerio
geotaxis
novelty
scototaxis
shoaling
thigmotaxis
zebrafish

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

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10.17816/RCF202123-133

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Galstyan, D. S., Kolesnikova, T. O., Kositsyn, Y. M., Zabegalov, K. N., Gubaidullina, M. A., Maslov, G. O., Demin, K. A., & Kalueff, A. V. (2022). Assessment of general locomotor activity and anxiety in zebrafish (Danio rerio) in the light-dark box (tank), the shoaling test, in the novel tank and the open field tests. Reviews on Clinical Pharmacology and Drug Therapy, 20(2), 123-133. https://doi.org/10.17816/RCF202123-133

@article{5211fd894e3846cfb45e767dc054b5f1,

title = "Assessment of general locomotor activity and anxiety in zebrafish (Danio rerio) in the light-dark box (tank), the shoaling test, in the novel tank and the open field tests",

abstract = "Anxiety is a complex and multifaceted neurobehavioral disorder that includes various forms of chronic pathological anxiety and fears, and is also the cause for various comorbid pathologies, such as depression or cardiovascular diseases. Behavioral testing of various model organisms, including the zebrafish (Danio rerio), is widely used to study neurobiological mechanisms of anxiety. Here, we discuss the novel tank test, the open field test, light-dark box and shoaling test that are widely used in translational biological psychiatry to characterize anxiety-related behavioral phenotypes in zebrafish.",

keywords = "anxiety, Danio rerio, geotaxis, novelty, scototaxis, shoaling, thigmotaxis, zebrafish",

author = "Galstyan, {David S.} and Kolesnikova, {Tatyana O.} and Kositsyn, {Yurii M.} and Zabegalov, {Konstantin N.} and Gubaidullina, {Mariya A.} and Maslov, {Gleb O.} and Demin, {Konstantin A.} and Kalueff, {Allan V.}",

year = "2022",

doi = "10.17816/RCF202123-133",

language = "English",

volume = "20",

pages = "123--133",

journal = "Reviews on Clinical Pharmacology and Drug Therapy",

issn = "1683-4100",

number = "2",

}

Galstyan, DS, Kolesnikova, TO, Kositsyn, YM, Zabegalov, KN, Gubaidullina, MA, Maslov, GO, Demin, KA & Kalueff, AV 2022, 'Assessment of general locomotor activity and anxiety in zebrafish (Danio rerio) in the light-dark box (tank), the shoaling test, in the novel tank and the open field tests', Reviews on Clinical Pharmacology and Drug Therapy, vol. 20, no. 2, pp. 123-133. https://doi.org/10.17816/RCF202123-133

Assessment of general locomotor activity and anxiety in zebrafish (Danio rerio) in the light-dark box (tank), the shoaling test, in the novel tank and the open field tests. / Galstyan, David S.; Kolesnikova, Tatyana O.; Kositsyn, Yurii M. et al.
In: Reviews on Clinical Pharmacology and Drug Therapy, Vol. 20, No. 2, 2022, p. 123-133.

Research output: Contribution to journal › Review article › peer-review

TY - JOUR

T1 - Assessment of general locomotor activity and anxiety in zebrafish (Danio rerio) in the light-dark box (tank), the shoaling test, in the novel tank and the open field tests

AU - Galstyan, David S.

AU - Kolesnikova, Tatyana O.

AU - Kositsyn, Yurii M.

AU - Zabegalov, Konstantin N.

AU - Gubaidullina, Mariya A.

AU - Maslov, Gleb O.

AU - Demin, Konstantin A.

AU - Kalueff, Allan V.

PY - 2022

Y1 - 2022

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AB - Anxiety is a complex and multifaceted neurobehavioral disorder that includes various forms of chronic pathological anxiety and fears, and is also the cause for various comorbid pathologies, such as depression or cardiovascular diseases. Behavioral testing of various model organisms, including the zebrafish (Danio rerio), is widely used to study neurobiological mechanisms of anxiety. Here, we discuss the novel tank test, the open field test, light-dark box and shoaling test that are widely used in translational biological psychiatry to characterize anxiety-related behavioral phenotypes in zebrafish.

KW - anxiety

KW - Danio rerio

KW - geotaxis

KW - novelty

KW - scototaxis

KW - shoaling

KW - thigmotaxis

KW - zebrafish

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U2 - 10.17816/RCF202123-133

DO - 10.17816/RCF202123-133

M3 - Review article

AN - SCOPUS:85164412783

SN - 1683-4100

VL - 20

SP - 123

EP - 133

JO - Reviews on Clinical Pharmacology and Drug Therapy

JF - Reviews on Clinical Pharmacology and Drug Therapy

IS - 2

ER -

Assessment of general locomotor activity and anxiety in zebrafish (Danio rerio) in the light-dark box (tank), the shoaling test, in the novel tank and the open field tests

Abstract

Keywords

UN SDGs

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