Anthocyanins: Multi-target agents for prevention and therapy of chronic diseases

Swathi Putta; Nagendra S. Yarla; Ilaria Peluso; Dinesh K. Tiwari; Gorlav Reddy; Priyanka V. Giri; Naresh Kumar; Ramarao Malla; Vijaya Rachel; P. Veera Bramhachari; Rama S.D. Reddy; Ramesh Bade; Mastan Mannarapu; George E. Barreto; Da Yong Lu; Vadim V. Tarasov; Vladimir N. Chubarev; Frederico F. Ribeiro; Luciana Scotti; Marcus T. Scotti; M. A. Kamal; Ghulam Md Ashraf; Gjumrakch Aliev; George Perry; Satyajit D. Sarker; Chinthalapally V. Rao; Anupam Bishayee

doi:10.2174/1381612823666170519151801

Anthocyanins: Multi-target agents for prevention and therapy of chronic diseases

Swathi Putta, Nagendra S. Yarla^*, Ilaria Peluso, Dinesh K. Tiwari, Gorlav Reddy, Priyanka V. Giri, Naresh Kumar, Ramarao Malla, Vijaya Rachel, P. Veera Bramhachari, Rama S.D. Reddy, Ramesh Bade, Mastan Mannarapu, George E. Barreto, Da Yong Lu, Vadim V. Tarasov, Vladimir N. Chubarev, Frederico F. Ribeiro, Luciana Scotti, Marcus T. ScottiM. A. Kamal, Ghulam Md Ashraf, Gjumrakch Aliev, George Perry, Satyajit D. Sarker, Chinthalapally V. Rao, Anupam Bishayee

^*Corresponding author for this work

Research output: Contribution to journal › Review article › peer-review

38 Citations (Scopus)

Abstract

Anthocyanins, a flavonoid class of polyphenols, are water soluble dark colored natural pigments found in fruits and vegetables. Owing to their wide distribution in plant materials, dietary consumption of anthocyanins is high compared to other flavonoids. Anthocyanins, due to their multifaceted medicinal properties are the active components in many herbal folk medicines. As in vitro and in vivo results, animal models, and clinical trials in various cell lines suggest, anthocyanins possess antioxidant, antidiabetic, antihyperlipidemic, anti-inflammatory, anticarcinogenic, antiulcer, and preventive activities against cardiovascular diseases. Additionally, anthocyanins exhibit chemotherapeutic, cardioprotective, hepatoprotective, and neuroprotective activities. In the diet, anthocyanins are absorbed in the stomach and intestinal cells and rapidly detected in the plasma. These promising properties of anthocyanins may well provide health benefits against chronic diseases.

Original language	English
Pages (from-to)	6321-6346
Number of pages	26
Journal	Current Pharmaceutical Design
Volume	23
Issue number	41
DOIs	https://doi.org/10.2174/1381612823666170519151801
Publication status	Published - 2017
Externally published	Yes

Keywords

Anthocyanins
Anti-inflammatory and anticarcinogenic activity
Antidiabetic
Antihyperlipidemic
Antioxidant
Multitarget therapeutic agents

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Access to Document

10.2174/1381612823666170519151801

Cite this

Putta, S., Yarla, N. S., Peluso, I., Tiwari, D. K., Reddy, G., Giri, P. V., Kumar, N., Malla, R., Rachel, V., Bramhachari, P. V., Reddy, R. S. D., Bade, R., Mannarapu, M., Barreto, G. E., Lu, D. Y., Tarasov, V. V., Chubarev, V. N., Ribeiro, F. F., Scotti, L., ... Bishayee, A. (2017). Anthocyanins: Multi-target agents for prevention and therapy of chronic diseases. Current Pharmaceutical Design, 23(41), 6321-6346. https://doi.org/10.2174/1381612823666170519151801

@article{f37014dd4ec1408cb27d626301e22adf,

title = "Anthocyanins: Multi-target agents for prevention and therapy of chronic diseases",

abstract = "Anthocyanins, a flavonoid class of polyphenols, are water soluble dark colored natural pigments found in fruits and vegetables. Owing to their wide distribution in plant materials, dietary consumption of anthocyanins is high compared to other flavonoids. Anthocyanins, due to their multifaceted medicinal properties are the active components in many herbal folk medicines. As in vitro and in vivo results, animal models, and clinical trials in various cell lines suggest, anthocyanins possess antioxidant, antidiabetic, antihyperlipidemic, anti-inflammatory, anticarcinogenic, antiulcer, and preventive activities against cardiovascular diseases. Additionally, anthocyanins exhibit chemotherapeutic, cardioprotective, hepatoprotective, and neuroprotective activities. In the diet, anthocyanins are absorbed in the stomach and intestinal cells and rapidly detected in the plasma. These promising properties of anthocyanins may well provide health benefits against chronic diseases.",

keywords = "Anthocyanins, Anti-inflammatory and anticarcinogenic activity, Antidiabetic, Antihyperlipidemic, Antioxidant, Multitarget therapeutic agents",

author = "Swathi Putta and Yarla, {Nagendra S.} and Ilaria Peluso and Tiwari, {Dinesh K.} and Gorlav Reddy and Giri, {Priyanka V.} and Naresh Kumar and Ramarao Malla and Vijaya Rachel and Bramhachari, {P. Veera} and Reddy, {Rama S.D.} and Ramesh Bade and Mastan Mannarapu and Barreto, {George E.} and Lu, {Da Yong} and Tarasov, {Vadim V.} and Chubarev, {Vladimir N.} and Ribeiro, {Frederico F.} and Luciana Scotti and Scotti, {Marcus T.} and Kamal, {M. A.} and Ashraf, {Ghulam Md} and Gjumrakch Aliev and George Perry and Sarker, {Satyajit D.} and Rao, {Chinthalapally V.} and Anupam Bishayee",

note = "Publisher Copyright: {\textcopyright} 2017 Bentham Science Publishers.",

year = "2017",

doi = "10.2174/1381612823666170519151801",

language = "English",

volume = "23",

pages = "6321--6346",

journal = "Current Pharmaceutical Design",

issn = "1381-6128",

number = "41",

}

Putta, S, Yarla, NS, Peluso, I, Tiwari, DK, Reddy, G, Giri, PV, Kumar, N, Malla, R, Rachel, V, Bramhachari, PV, Reddy, RSD, Bade, R, Mannarapu, M, Barreto, GE, Lu, DY, Tarasov, VV, Chubarev, VN, Ribeiro, FF, Scotti, L, Scotti, MT, Kamal, MA, Ashraf, GM, Aliev, G, Perry, G, Sarker, SD, Rao, CV & Bishayee, A 2017, 'Anthocyanins: Multi-target agents for prevention and therapy of chronic diseases', Current Pharmaceutical Design, vol. 23, no. 41, pp. 6321-6346. https://doi.org/10.2174/1381612823666170519151801

TY - JOUR

T1 - Anthocyanins

T2 - Multi-target agents for prevention and therapy of chronic diseases

AU - Putta, Swathi

AU - Yarla, Nagendra S.

AU - Peluso, Ilaria

AU - Tiwari, Dinesh K.

AU - Reddy, Gorlav

AU - Giri, Priyanka V.

AU - Kumar, Naresh

AU - Malla, Ramarao

AU - Rachel, Vijaya

AU - Bramhachari, P. Veera

AU - Reddy, Rama S.D.

AU - Bade, Ramesh

AU - Mannarapu, Mastan

AU - Barreto, George E.

AU - Lu, Da Yong

AU - Tarasov, Vadim V.

AU - Chubarev, Vladimir N.

AU - Ribeiro, Frederico F.

AU - Scotti, Luciana

AU - Scotti, Marcus T.

AU - Kamal, M. A.

AU - Ashraf, Ghulam Md

AU - Aliev, Gjumrakch

AU - Perry, George

AU - Sarker, Satyajit D.

AU - Rao, Chinthalapally V.

AU - Bishayee, Anupam

PY - 2017

Y1 - 2017

N2 - Anthocyanins, a flavonoid class of polyphenols, are water soluble dark colored natural pigments found in fruits and vegetables. Owing to their wide distribution in plant materials, dietary consumption of anthocyanins is high compared to other flavonoids. Anthocyanins, due to their multifaceted medicinal properties are the active components in many herbal folk medicines. As in vitro and in vivo results, animal models, and clinical trials in various cell lines suggest, anthocyanins possess antioxidant, antidiabetic, antihyperlipidemic, anti-inflammatory, anticarcinogenic, antiulcer, and preventive activities against cardiovascular diseases. Additionally, anthocyanins exhibit chemotherapeutic, cardioprotective, hepatoprotective, and neuroprotective activities. In the diet, anthocyanins are absorbed in the stomach and intestinal cells and rapidly detected in the plasma. These promising properties of anthocyanins may well provide health benefits against chronic diseases.

AB - Anthocyanins, a flavonoid class of polyphenols, are water soluble dark colored natural pigments found in fruits and vegetables. Owing to their wide distribution in plant materials, dietary consumption of anthocyanins is high compared to other flavonoids. Anthocyanins, due to their multifaceted medicinal properties are the active components in many herbal folk medicines. As in vitro and in vivo results, animal models, and clinical trials in various cell lines suggest, anthocyanins possess antioxidant, antidiabetic, antihyperlipidemic, anti-inflammatory, anticarcinogenic, antiulcer, and preventive activities against cardiovascular diseases. Additionally, anthocyanins exhibit chemotherapeutic, cardioprotective, hepatoprotective, and neuroprotective activities. In the diet, anthocyanins are absorbed in the stomach and intestinal cells and rapidly detected in the plasma. These promising properties of anthocyanins may well provide health benefits against chronic diseases.

KW - Anthocyanins

KW - Anti-inflammatory and anticarcinogenic activity

KW - Antidiabetic

KW - Antihyperlipidemic

KW - Antioxidant

KW - Multitarget therapeutic agents

UR - http://www.scopus.com/inward/record.url?scp=85046739197&partnerID=8YFLogxK

U2 - 10.2174/1381612823666170519151801

DO - 10.2174/1381612823666170519151801

M3 - Review article

C2 - 28741457

AN - SCOPUS:85046739197

SN - 1381-6128

VL - 23

SP - 6321

EP - 6346

JO - Current Pharmaceutical Design

JF - Current Pharmaceutical Design

IS - 41

ER -

Anthocyanins: Multi-target agents for prevention and therapy of chronic diseases

Abstract

Keywords

UN SDGs

Access to Document

Other files and links

Fingerprint

Cite this