Zebrafish Models for Stress Research

Murilo S. de Abreu; Konstantin A. Demin; Tamara G. Amstislavskaya; Tatyana Strekalova; Allan V. Kalueff

doi:10.1016/B978-0-12-813156-5.00024-8

Zebrafish Models for Stress Research

Murilo S. de Abreu, Konstantin A. Demin, Tamara G. Amstislavskaya, Tatyana Strekalova, Allan V. Kalueff

Research output: Chapter in Book or Report/Conference proceeding › Chapter › peer-review

4 Citations (Scopus)

Abstract

Zebrafish (Danio rerio) are rapidly emerging as a promising new model species in stress research, characterized by complex behaviors in all major neurobehavioral domains and high genetic and physiological similarity with humans. Here, we summarize common neurobehavioral models of zebrafish stress and discuss their relevance to studying the pathobiology of stress and stress-related human disorders. Zebrafish behavioral tests and methods of stress induction are developing at a rapid pace, fostering our better understanding of complex biological phenomena, including normal and pathological brain functioning and their pharmacological and nonpharmacological correction.

Original language	English
Title of host publication	Stress
Subtitle of host publication	Genetics, Epigenetics and Genomics Volume 4: Handbook of Stress
Publisher	Elsevier
Pages	263-268
Number of pages	6
ISBN (Electronic)	9780128131565
DOIs	https://doi.org/10.1016/B978-0-12-813156-5.00024-8
Publication status	Published - 1 Jan 2020
Externally published	Yes

Keywords

Acute stress
Behavior
Chronic stress
Cortisol
Stress disorders
Zebrafish

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10.1016/B978-0-12-813156-5.00024-8

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title = "Zebrafish Models for Stress Research",

abstract = "Zebrafish (Danio rerio) are rapidly emerging as a promising new model species in stress research, characterized by complex behaviors in all major neurobehavioral domains and high genetic and physiological similarity with humans. Here, we summarize common neurobehavioral models of zebrafish stress and discuss their relevance to studying the pathobiology of stress and stress-related human disorders. Zebrafish behavioral tests and methods of stress induction are developing at a rapid pace, fostering our better understanding of complex biological phenomena, including normal and pathological brain functioning and their pharmacological and nonpharmacological correction.",

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T1 - Zebrafish Models for Stress Research

AU - de Abreu, Murilo S.

AU - Demin, Konstantin A.

AU - Amstislavskaya, Tamara G.

AU - Strekalova, Tatyana

AU - Kalueff, Allan V.

PY - 2020/1/1

Y1 - 2020/1/1

N2 - Zebrafish (Danio rerio) are rapidly emerging as a promising new model species in stress research, characterized by complex behaviors in all major neurobehavioral domains and high genetic and physiological similarity with humans. Here, we summarize common neurobehavioral models of zebrafish stress and discuss their relevance to studying the pathobiology of stress and stress-related human disorders. Zebrafish behavioral tests and methods of stress induction are developing at a rapid pace, fostering our better understanding of complex biological phenomena, including normal and pathological brain functioning and their pharmacological and nonpharmacological correction.

AB - Zebrafish (Danio rerio) are rapidly emerging as a promising new model species in stress research, characterized by complex behaviors in all major neurobehavioral domains and high genetic and physiological similarity with humans. Here, we summarize common neurobehavioral models of zebrafish stress and discuss their relevance to studying the pathobiology of stress and stress-related human disorders. Zebrafish behavioral tests and methods of stress induction are developing at a rapid pace, fostering our better understanding of complex biological phenomena, including normal and pathological brain functioning and their pharmacological and nonpharmacological correction.

KW - Acute stress

KW - Behavior

KW - Chronic stress

KW - Cortisol

KW - Stress disorders

KW - Zebrafish

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M3 - Chapter

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SP - 263

EP - 268

BT - Stress

PB - Elsevier

ER -

Zebrafish Models for Stress Research

Abstract

Keywords

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