Abstract
Let's do the twist: The first twisted bis-amide (see figure) is obtained by the benzylic oxidation of Tröger's base (TB). Kinetic studies of its acidic hydrolysis reveal that the hydrolysis is to a large extent funneled through doubly protonated species.
Original language | English |
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Pages (from-to) | 1038-1042 |
Number of pages | 5 |
Journal | Chemistry - A European Journal |
Volume | 18 |
Issue number | 4 |
DOIs | |
Publication status | Published - 23 Jan 2012 |
Externally published | Yes |
Keywords
- Tröger's base
- X-ray structures
- hydrolysis
- oxidation
- twisted amides