Synthesis and chemical transformations of 3-acetyl-4-hydroxyquinolin-2(1H)-one and its N-substituted derivatives: bird’s eye view

Moaz M. Abdou; Zeynel Seferoğlu; Mahmoud Fathy; Takashiro Akitsu; Mamoru Koketsu; Ruba Kellow; Eric Amigues

doi:10.1007/s11164-018-3652-1

Synthesis and chemical transformations of 3-acetyl-4-hydroxyquinolin-2(1H)-one and its N-substituted derivatives: bird’s eye view

Moaz M. Abdou^*, Zeynel Seferoğlu, Mahmoud Fathy, Takashiro Akitsu, Mamoru Koketsu, Ruba Kellow, Eric Amigues

^*Corresponding author for this work

Department of Chemistry

Research output: Contribution to journal › Review article › peer-review

13 Citations (Scopus)

Abstract

The chemistry of 3-acetyl-4-hydroxyquinolin-2(1H)-ones has attracted increased attention in both synthetic organic and medicinal chemistry, as numerous advancements in the use of this family of important compounds seems to be of considerable value. This account summarizes the results from the literature focusing on synthesis of 3-acetyl-4-hydroxyquinolin-2(1H)-ones as well as their reactions are also discussed.

Original language	English
Pages (from-to)	919-934
Number of pages	16
Journal	Research on Chemical Intermediates
Volume	45
Issue number	3
DOIs	https://doi.org/10.1007/s11164-018-3652-1
Publication status	Published - 15 Mar 2019

Keywords

3-Acetyl-4-hydroxyquinolin-2(1H)-one
Chemical reactivity
Condensation
Cyclization
Heterocycles
Synthesis

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abstract = "The chemistry of 3-acetyl-4-hydroxyquinolin-2(1H)-ones has attracted increased attention in both synthetic organic and medicinal chemistry, as numerous advancements in the use of this family of important compounds seems to be of considerable value. This account summarizes the results from the literature focusing on synthesis of 3-acetyl-4-hydroxyquinolin-2(1H)-ones as well as their reactions are also discussed.",

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AU - Abdou, Moaz M.

AU - Seferoğlu, Zeynel

AU - Fathy, Mahmoud

AU - Akitsu, Takashiro

AU - Koketsu, Mamoru

AU - Kellow, Ruba

AU - Amigues, Eric

PY - 2019/3/15

Y1 - 2019/3/15

N2 - The chemistry of 3-acetyl-4-hydroxyquinolin-2(1H)-ones has attracted increased attention in both synthetic organic and medicinal chemistry, as numerous advancements in the use of this family of important compounds seems to be of considerable value. This account summarizes the results from the literature focusing on synthesis of 3-acetyl-4-hydroxyquinolin-2(1H)-ones as well as their reactions are also discussed.

AB - The chemistry of 3-acetyl-4-hydroxyquinolin-2(1H)-ones has attracted increased attention in both synthetic organic and medicinal chemistry, as numerous advancements in the use of this family of important compounds seems to be of considerable value. This account summarizes the results from the literature focusing on synthesis of 3-acetyl-4-hydroxyquinolin-2(1H)-ones as well as their reactions are also discussed.

KW - 3-Acetyl-4-hydroxyquinolin-2(1H)-one

KW - Chemical reactivity

KW - Condensation

KW - Cyclization

KW - Heterocycles

KW - Synthesis

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Synthesis and chemical transformations of 3-acetyl-4-hydroxyquinolin-2(1H)-one and its N-substituted derivatives: bird’s eye view

Abstract

Keywords

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