Switchable solvents consisting of amidine/alcohol or guanidine/alcohol mixtures

Lam Phan, Daniel Chiu, David J. Heldebrant, Hillary Huttenhower, Ejae John, Xiaowang Li, Pamela Pollet, Ruiyao Wang, Charles A. Eckert, Charles L. Liotta, Philip G. Jessop*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

240 Citations (Scopus)


Liquids that consist of a mixture of an alcohol and either an amidine or a guanidine have been developed to switch from a low-polarity form to a high-polarity ionic liquid upon treatment with CO2 at atmospheric pressure. Treatment with N2 and/or mild heat (50-60°C) reverses the process. These liquids can be used as switchable solvents to dissolve and then precipitate a solute or to dissolve reagents for a chemical synthesis and then precipitate the product.

Original languageEnglish
Pages (from-to)539-545
Number of pages7
JournalIndustrial and Engineering Chemistry Research
Issue number3
Publication statusPublished - 6 Feb 2008
Externally publishedYes

Cite this