Sparse autoencoder based deep neural network for voxelwise detection of cerebral microbleed

Yu Dong Zhang, Xiao Xia Hou, Yi Ding Lv, Hong Chen, Yin Zhang, Shui Hua Wang*

*Corresponding author for this work

Research output: Chapter in Book or Report/Conference proceedingConference Proceedingpeer-review

20 Citations (Scopus)

Abstract

In order to detect cerebral microbleed more efficiently, we developed a novel computer-aided detection method based on susceptibility-weighted imaging. We enrolled five CADASIL patients and five healthy controls. We used a 20x20 neighboring window to generate samples on each slice of the volumetric brain images. The sparse autoencoder (SAE) was used to unsupervised feature learning. Then, a deep neural network was established using the learned features. The results over 10x10-fold cross validation showed our method yielded a sensitivity of 93.20±1.37%, a specificity of 93.25±1.38%, and an accuracy of 93.22±1.37%. Our result is better than Roy's method, which was proposed in 2015.

Original languageEnglish
Title of host publicationProceedings - 22nd IEEE International Conference on Parallel and Distributed Systems, ICPADS 2016
EditorsXiaofei Liao, Robert Lovas, Xipeng Shen, Ran Zheng
PublisherIEEE Computer Society
Pages1229-1232
Number of pages4
ISBN (Electronic)9781509044573
DOIs
Publication statusPublished - 2 Jul 2016
Externally publishedYes
Event22nd IEEE International Conference on Parallel and Distributed Systems, ICPADS 2016 - Wuhan, Hubei, China
Duration: 13 Dec 201616 Dec 2016

Publication series

NameProceedings of the International Conference on Parallel and Distributed Systems - ICPADS
Volume0
ISSN (Print)1521-9097

Conference

Conference22nd IEEE International Conference on Parallel and Distributed Systems, ICPADS 2016
Country/TerritoryChina
CityWuhan, Hubei
Period13/12/1616/12/16

Keywords

  • Cerebral microbleed
  • Cross validation
  • Deep neural network
  • Sparse autoencoder
  • Susceptibility weighted imaging

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