Solvent-modulated reactivity of PCl3 with amines

Eric Jean Amigues, Christopher Hardacre*, Gillian Keane, Marie Eugenie Migaud

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)


The reactivity of phosphorus trichloride towards amines in ionic liquids has been investigated and compared with that in conventional organic solvents. In addition to easing the synthetic procedures thus far required for the preparation of aminochlorophosphines in molecular solvents, for example the ability to operate at 20 °C, under non-anhydrous and high concentration conditions with short reaction times and rapid addition of reagents, bis((trifluoromethyl)sulfonyl)imide-based ionic liquids offer a tight control over the selectivity during the reaction and offer access to monoamination and bisamination products in high yields and chemoselectively. Furthermore, these ionic liquids offer a unique storage medium for these highly moisture sensitive aminochlorophosphines.

Original languageEnglish
Pages (from-to)660-666
Number of pages7
JournalGreen Chemistry
Issue number6
Publication statusPublished - 1 Jun 2008
Externally publishedYes

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