Single source precursor synthesized CuS nanoparticles for NIR phototherapy of cancer and photodegradation of organic carcinogen

Mehwish Arshad, Zhaojie Wang, Jamal Abdul Nasir, Eric Amador, Mingwu Jin, Haibin Li, Zhigang Chen, Zia ur Rehman*, Wei Chen

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

22 Citations (Scopus)

Abstract

Herein, we report cost effective and body compatible CuS nanoparticles (NPs) derived from a single source precursor as photothermal agent for healing deep cancer and photocatalytic remediation of organic carcinogens. These NPs efficiently kill MCF7 cells (both in vivo and in vitro) under NIR irradiation by raising the temperature of tumor cells. Such materials can be used for the treatment of deep cancer as they can produce a heating effect using high wavelength and deeply penetrating NIR radiation. Furthermore, CuS NPs under solar light irradiation efficiently convert p-nitrophenol (PNP), an environmental carcinogen, to p-aminophenol (PAP) of pharmaceutical implication. In a nutshell, CuS can be used for the treatment of deep cancer and for the remediation of carcinogenic pollutants. There seems an intrinsic connection between the two functions of CuS NPs that need to be explored in length.

Original languageEnglish
Article number112084
JournalJournal of Photochemistry and Photobiology B: Biology
Volume214
DOIs
Publication statusPublished - Jan 2021
Externally publishedYes

Keywords

  • Anticancer
  • Carcinogen
  • CuS nanoparticles
  • Photocatalysis
  • Phototherapy

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