Regulation of Ribosome Biogenesis during Skeletal Muscle Hypertrophy

Hyo Gun Kim, Bin Guo, Gustavo A. Nader*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

17 Citations (Scopus)

Abstract

An increase in ribosomal capacity is a hallmark of the hypertrophying muscle. We review evidence demonstrating that transcription of ribosomal RNA genes is necessary for the increase in ribosomal capacity, and this is critical for muscle growth in human and animal models of hypertrophy.

Original languageEnglish
Pages (from-to)91-97
Number of pages7
JournalExercise and Sport Sciences Reviews
Volume47
Issue number2
DOIs
Publication statusPublished - 1 Apr 2019
Externally publishedYes

Keywords

  • hypertrophy
  • keletal muscle
  • resistance exercise
  • ribosome biogenesis
  • transcription

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