Quality control of cellular protein in neurodegenerative disorders

Md Sahab Uddin*, Ghulam Md Ashraf

*Corresponding author for this work

Research output: Book/Report/Edited volumeBookpeer-review

11 Citations (Scopus)

Abstract

Protein misfolding and aggregation are hallmarks of several neurodegenerative proteinopathies. Though multiple factors like aging, oxidative stress, mitochondrial dysfunction, proteotoxic insults, genetic inconsistency, etc. are responsible for the dysfunction of the neuronal protein quality control system, targeting protein quality control has become an auspicious approach to halt the propagation of neurodegeneration. Quality Control of Cellular Protein in Neurodegenerative Disorders provides diverse aspects exploring the role of the protein quality control in neurodegenerative disorders and potential therapeutic strategies to combat the development and propagation of neurodegeneration. Featuring coverage on a broad range of topics such as molecular chaperones, protein misfolding, and stress signaling, this book is ideally designed for neurobiologists, neuropsychologists, neurophysiologists, medical professionals, neuropathologists, researchers, academicians, students, and practitioners engaged in studies of the protein quality control system in neuronal cells.

Original languageEnglish
PublisherIGI Global
Number of pages515
ISBN (Electronic)9781799813187
ISBN (Print)9781799813170
DOIs
Publication statusPublished - 14 Feb 2020
Externally publishedYes

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