TY - JOUR
T1 - Neurostimulatory and ablative treatment options in major depressive disorder
T2 - A systematic review
AU - Andrade, Pablo
AU - Noblesse, Lieke H.M.
AU - Temel, Yasin
AU - Ackermans, Linda
AU - Lim, Lee W.
AU - Steinbusch, Harry W.M.
AU - Visser-Vandewalle, Veerle
PY - 2010/4
Y1 - 2010/4
N2 - Introduction Major depressive disorder is one of the most disabling and common diagnoses amongst psychiatric disorders, with a current worldwide prevalence of 5-10% of the general population and up to 20-25% for the lifetime period. Historical perspective Nowadays, conventional treatment includes psychotherapy and pharmacotherapy; however, more than 60% of the treated patients respond unsatisfactorily, and almost one fifth becomes refractory to these therapies at long-term follow-up. Nonpharmacological techniques Growing social incapacity and economic burdens make the medical community strive for better therapies, with fewer complications. Various nonpharmacological techniques like electroconvulsive therapy, vagus nerve stimulation, transcranial magnetic stimulation, lesion surgery, and deep brain stimulation have been developed for this purpose. Discussion We reviewed the literature from the beginning of the twentieth century until July 2009 and described the early clinical effects and main reported complications of these methods.
AB - Introduction Major depressive disorder is one of the most disabling and common diagnoses amongst psychiatric disorders, with a current worldwide prevalence of 5-10% of the general population and up to 20-25% for the lifetime period. Historical perspective Nowadays, conventional treatment includes psychotherapy and pharmacotherapy; however, more than 60% of the treated patients respond unsatisfactorily, and almost one fifth becomes refractory to these therapies at long-term follow-up. Nonpharmacological techniques Growing social incapacity and economic burdens make the medical community strive for better therapies, with fewer complications. Various nonpharmacological techniques like electroconvulsive therapy, vagus nerve stimulation, transcranial magnetic stimulation, lesion surgery, and deep brain stimulation have been developed for this purpose. Discussion We reviewed the literature from the beginning of the twentieth century until July 2009 and described the early clinical effects and main reported complications of these methods.
KW - Deep brain stimulation
KW - Electroconvulsive therapy
KW - Major depressive disorder
KW - Psychosurgery
KW - Transcranial magnetic stimulation
KW - Vagus nerve stimulation
UR - http://www.scopus.com/inward/record.url?scp=77953026942&partnerID=8YFLogxK
U2 - 10.1007/s00701-009-0589-6
DO - 10.1007/s00701-009-0589-6
M3 - Review article
C2 - 20101419
AN - SCOPUS:77953026942
SN - 0001-6268
VL - 152
SP - 565
EP - 577
JO - Acta Neurochirurgica
JF - Acta Neurochirurgica
IS - 4
ER -