Neuropharmacology of Aggression in Model Systems: The Zebrafish as a New Narrative

Murilo S.de Abreu*, Konstantin A. Demin, Fabiano V. Costa, Konstantin N. Zabegalov, Ana C.V.V. Giacomini, Allan V. Kalueff

*Corresponding author for this work

Research output: Chapter in Book or Report/Conference proceedingChapterpeer-review

Abstract

Zebrafish (Danio rerio) are rapidly becoming a powerful new model organism for neurobehavioral and neuropharmacological research, including translational studies of aggression. Here, we review zebrafish aggression behavioral phenotypes, as well as pharmacological and genetic models of aggression in this aquatic species, and also discuss how zebrafish models may foster future discoveries of potential therapeutic agents for reducing aggressive phenotypes.

Original languageEnglish
Title of host publicationHandbook of Anger, Aggression, and Violence
PublisherSpringer International Publishing
Pages2689-2699
Number of pages11
ISBN (Electronic)9783031315473
ISBN (Print)9783031315466
DOIs
Publication statusPublished - 1 Jan 2023
Externally publishedYes

Keywords

  • Aggression
  • Pharmacological modulation
  • Pre-clinical models
  • Zebrafish

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