@inbook{27dd7c5812e2475f8b8b08e840f3f608,
title = "Neuromodulation in Psychiatric Disorders",
abstract = "Psychiatric disorders are worldwide a common cause of severe and long-term disability and socioeconomic burden. The management of patients with psychiatric disorders consists of drug therapy and/or psychotherapy. However, in some patients, these treatment modalities do not produce sufficient therapeutic effects or induce intolerable side effects. For these patients, neuromodulation has been suggested as a potential treatment modality. Neuromodulation includes deep brain stimulation, vagal nerve stimulation, and transcranial magnetic and electrical stimulation. The rationale for neuromodulation is derived from the research identifying neurobiologically localized substrates for refractory psychiatric symptoms. Here, we review the clinical data on neuromodulation in the major psychiatric disorders. Relevant data from animal models will also be discussed to explain the neurobiological basis of the therapy.",
keywords = "Addiction, Alzheimer's disease, Deep brain stimulation, Depression, Neuromodulation, Obsessive-compulsive disorder, Psychiatry, Tourette syndrome, Transcranial stimulation, Vagus nerve stimulation",
author = "Yasin Temel and Hescham, {Sarah A.} and Ali Jahanshahi and Janssen, {Marcus L.F.} and Tan, {Sonny K.H.} and {van Overbeeke}, {Jacobus J.} and Linda Ackermans and Mayke Oosterloo and Annelien Duits and Leentjens, {Albert F.G.} and Lim, {Lee Wei}",
year = "2012",
doi = "10.1016/B978-0-12-404706-8.00015-2",
language = "English",
series = "International Review of Neurobiology",
publisher = "Academic Press Inc.",
pages = "283--314",
booktitle = "International Review of Neurobiology",
}