Neuroimmunology: Translational lessons from zebrafish models

Murilo S. de Abreu*, Ana C.V.V. Giacomini, Allan V. Kalueff

*Corresponding author for this work

Research output: Chapter in Book or Report/Conference proceedingChapterpeer-review


Zebrafish (Danio rerio) share high genetic and physiological similarity with mammals and possess complex phenotypes in all major, evolutionarily conserved, neurobehavioral domains. Zebrafish are also rapidly emerging as a promising novel model organism in neuroimmunology and psychoneuroimmunology research. Here, we summarize neuroimmune mechanisms and their experimental modulation in zebrafish, and discuss some other relevant physiological aspects, such as the gut microbiota-brain interplay, as well as the translational insights from zebrafish neuroimmune models.

Original languageEnglish
Title of host publicationTranslational Neuroimmunology
Subtitle of host publicationNeuroinflammation: Volume 7
Number of pages9
ISBN (Electronic)9780323858410
ISBN (Print)9780323900713
Publication statusPublished - 1 Jan 2023
Externally publishedYes


  • Behavior
  • Genetic models
  • Gut microbiota
  • Stress
  • The immune system
  • Zebrafish


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