MRI and CT compatible asymmetric bilayer hydrogel electrodes for EEG-based brain activity monitoring

Guoqiang Ren, Mingxuan Zhang, Liping Zhuang, Lianhui Li, Shunying Zhao, Jinxiu Guo, Yinchao Zhao, Zhaoxiang Peng, Jiangfan Lian, Botao Liu, Jingyun Ma, Xiaodong Hu, Zhewei Zhang, Ting Zhang*, Qifeng Lu*, Mingming Hao*

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

Abstract

The exploration of multi-dimensional brain activity with high temporal and spatial resolution is of great significance in the diagnosis of neurological disease and the study of brain science. Although the integration of electroencephalogram (EEG) with magnetic resonance imaging (MRI) and computed tomography (CT) provides a potential solution to achieve a brain-functional image with high spatiotemporal resolution, the critical issues of interface stability and magnetic compatibility remain challenging. Therefore, in this research, we proposed a conductive hydrogel EEG electrode with an asymmetrical bilayer structure, which shows the potential to overcome the challenges. Benefiting from the bilayer structure with different moduli, the hydrogel electrode exhibits high biological and mechanical compatibility with the heterogeneous brain-electrode interface. As a result, the impedance can be reduced compared with conventional metal electrodes. In addition, the hydrogel-based ionic conductive electrodes, which are free from metal conductors, are compatible with MRI and CT. Therefore, they can obtain high spatiotemporal resolution multi-dimensional brain information in clinical settings. The research outcome provides a new approach for establishing a platform for early diagnosis of brain diseases and the study of brain science. (Figure presented.)

Original languageEnglish
Article number156
JournalMicrosystems and Nanoengineering
Volume10
Issue number1
DOIs
Publication statusPublished - Dec 2024

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