Mini-review: Mechanisms of neuroprotective action of vitamin D3

A. V. Kalueff*, K. O. Eremin, P. Tuohimaa

*Corresponding author for this work

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)


This review considers modern data on the mechanisms underlying the neuroprotective effect of the neurosteroid vitamin D3 and its receptors in the nervous system. Special attention is paid to Ca2+ regulation, stimulation of neurotrophin release, interaction with reactive oxygen and nitrogen species, and neuroimmunomodulatory effects of calcitriol, the main biologically active form of vitamin D3, in the nervous system.

Original languageEnglish
Pages (from-to)907-911
Number of pages5
Issue number7
Publication statusPublished - 2004
Externally publishedYes


  • Calcitriol
  • Nervous system
  • Neuroprotection
  • Vitamin D


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