Mini-review: Mechanisms of neuroprotective action of vitamin D3

A. V. Kalueff; K. O. Eremin; P. Tuohimaa

Mini-review: Mechanisms of neuroprotective action of vitamin D₃

A. V. Kalueff^*, K. O. Eremin, P. Tuohimaa

^*Corresponding author for this work

Ctr. of Physiol. and Biochem. Res.

Research output: Contribution to journal › Article › peer-review

5 Citations (Scopus)

Abstract

This review considers modern data on the mechanisms underlying the neuroprotective effect of the neurosteroid vitamin D₃ and its receptors in the nervous system. Special attention is paid to Ca²⁺ regulation, stimulation of neurotrophin release, interaction with reactive oxygen and nitrogen species, and neuroimmunomodulatory effects of calcitriol, the main biologically active form of vitamin D₃, in the nervous system.

Original language	English
Pages (from-to)	907-911
Number of pages	5
Journal	Biokhimiya
Volume	69
Issue number	7
Publication status	Published - 2004
Externally published	Yes

Keywords

Calcitriol
Nervous system
Neuroprotection
Vitamin D

Cite this

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title = "Mini-review: Mechanisms of neuroprotective action of vitamin D3",

abstract = "This review considers modern data on the mechanisms underlying the neuroprotective effect of the neurosteroid vitamin D3 and its receptors in the nervous system. Special attention is paid to Ca2+ regulation, stimulation of neurotrophin release, interaction with reactive oxygen and nitrogen species, and neuroimmunomodulatory effects of calcitriol, the main biologically active form of vitamin D3, in the nervous system.",

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journal = "Biokhimiya",

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T2 - Mechanisms of neuroprotective action of vitamin D3

AU - Kalueff, A. V.

AU - Eremin, K. O.

AU - Tuohimaa, P.

PY - 2004

Y1 - 2004

N2 - This review considers modern data on the mechanisms underlying the neuroprotective effect of the neurosteroid vitamin D3 and its receptors in the nervous system. Special attention is paid to Ca2+ regulation, stimulation of neurotrophin release, interaction with reactive oxygen and nitrogen species, and neuroimmunomodulatory effects of calcitriol, the main biologically active form of vitamin D3, in the nervous system.

AB - This review considers modern data on the mechanisms underlying the neuroprotective effect of the neurosteroid vitamin D3 and its receptors in the nervous system. Special attention is paid to Ca2+ regulation, stimulation of neurotrophin release, interaction with reactive oxygen and nitrogen species, and neuroimmunomodulatory effects of calcitriol, the main biologically active form of vitamin D3, in the nervous system.

KW - Calcitriol

KW - Nervous system

KW - Neuroprotection

KW - Vitamin D

UR - http://www.scopus.com/inward/record.url?scp=5644238159&partnerID=8YFLogxK

M3 - Article

AN - SCOPUS:5644238159

SN - 0320-9725

VL - 69

SP - 907

EP - 911

JO - Biokhimiya

JF - Biokhimiya

IS - 7

ER -

Mini-review: Mechanisms of neuroprotective action of vitamin D₃

Abstract

Keywords

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