TY - JOUR
T1 - Iron-catalyzed cross-coupling of secondary alkyl chloride and the alkynes grignard reagent
AU - Jia, Wan
AU - Zhao, Lizhi
AU - Wei, Hengxu
AU - Zhu, Lindong
AU - Fu, Lei
AU - Chen, Weichun
N1 - Publisher Copyright:
© 2016 Chinese Chemical Society & SIOC, CAS.
PY - 2016/5/1
Y1 - 2016/5/1
N2 - A green, practical and efficient iron-catalyzed, base free cross-coupling reaction of non-activated secondary alkyl halides with the alkynes Grignard reagent has been developed to afford a variety of alkyl alkynes in high yields, using iron(III) chlorides as catalyst. This approach is quick and easy to operate. It exhibits promising in industry since utilizing the low-cost iron as a catalyst instead of expensive palladium or nickel.
AB - A green, practical and efficient iron-catalyzed, base free cross-coupling reaction of non-activated secondary alkyl halides with the alkynes Grignard reagent has been developed to afford a variety of alkyl alkynes in high yields, using iron(III) chlorides as catalyst. This approach is quick and easy to operate. It exhibits promising in industry since utilizing the low-cost iron as a catalyst instead of expensive palladium or nickel.
KW - Alkynes Grignard reagents
KW - Cross-coupling reactions
KW - Green chemistry
KW - Iron-catalyzed
KW - Secondary alkyl choloride
UR - http://www.scopus.com/inward/record.url?scp=84971278431&partnerID=8YFLogxK
U2 - 10.6023/cjoc201510031
DO - 10.6023/cjoc201510031
M3 - Article
AN - SCOPUS:84971278431
SN - 0253-2786
VL - 36
SP - 1060
EP - 1064
JO - Chinese Journal of Organic Chemistry
JF - Chinese Journal of Organic Chemistry
IS - 5
ER -