TY - GEN
T1 - Interoperable multi-modal data analysis platform for Alzheimer's disease management
AU - Pang, Zhen
AU - Zhang, Shuhao
AU - Yang, Yun
AU - Qi, Jun
AU - Yang, Po
N1 - Publisher Copyright:
© 2020 IEEE.
PY - 2020/12
Y1 - 2020/12
N2 - Neurological diseases are generating a wealth of data that can provide valuable insights into disease prediction and auxiliary diagnosis. There is a lack of specialized and standardized disease data analysis platforms that provide the technical approach to support the entire data analysis, namely data selection, management, analysis, visualization and sharing. This paper introduces a platform for the display and analysis of neurological research data, with a focus on Alzheimer's disease (AD), and presents the technical architecture of the AD data analysis platform. The platform provides a technical solution for analyzing AD data from multiple sources, thereby increasing the utilization and value of multi-modal data. A key aspect is the annotation and interpretation of medical raw data, as well as statistical analysis and visualization of MRI data. More importantly, another aspect is to classify through algorithm analysis to effectively predict the disease, so as to achieve the effect of auxiliary diagnosis. We use the data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database to train and test the classifier, as well as annotate and display the private data about AD obtained from the neurology department of the hospital. The design of the proposed network platform is extensible and can be easily adapted to other neurological diseases.
AB - Neurological diseases are generating a wealth of data that can provide valuable insights into disease prediction and auxiliary diagnosis. There is a lack of specialized and standardized disease data analysis platforms that provide the technical approach to support the entire data analysis, namely data selection, management, analysis, visualization and sharing. This paper introduces a platform for the display and analysis of neurological research data, with a focus on Alzheimer's disease (AD), and presents the technical architecture of the AD data analysis platform. The platform provides a technical solution for analyzing AD data from multiple sources, thereby increasing the utilization and value of multi-modal data. A key aspect is the annotation and interpretation of medical raw data, as well as statistical analysis and visualization of MRI data. More importantly, another aspect is to classify through algorithm analysis to effectively predict the disease, so as to achieve the effect of auxiliary diagnosis. We use the data from the Alzheimer's Disease Neuroimaging Initiative (ADNI) database to train and test the classifier, as well as annotate and display the private data about AD obtained from the neurology department of the hospital. The design of the proposed network platform is extensible and can be easily adapted to other neurological diseases.
KW - Alzheimer's disease
KW - Auxiliary diagnosis
KW - Disease prediction
KW - MRI
KW - Platform
UR - http://www.scopus.com/inward/record.url?scp=85108021790&partnerID=8YFLogxK
U2 - 10.1109/ISPA-BDCloud-SocialCom-SustainCom51426.2020.00196
DO - 10.1109/ISPA-BDCloud-SocialCom-SustainCom51426.2020.00196
M3 - Conference Proceeding
AN - SCOPUS:85108021790
T3 - Proceedings - 2020 IEEE International Symposium on Parallel and Distributed Processing with Applications, 2020 IEEE International Conference on Big Data and Cloud Computing, 2020 IEEE International Symposium on Social Computing and Networking and 2020 IEEE International Conference on Sustainable Computing and Communications, ISPA-BDCloud-SocialCom-SustainCom 2020
SP - 1321
EP - 1327
BT - Proceedings - 2020 IEEE International Symposium on Parallel and Distributed Processing with Applications, 2020 IEEE International Conference on Big Data and Cloud Computing, 2020 IEEE International Symposium on Social Computing and Networking and 2020 IEEE International Conference on Sustainable Computing and Communications, ISPA-BDCloud-SocialCom-SustainCom 2020
A2 - Hu, Jia
A2 - Min, Geyong
A2 - Georgalas, Nektarios
A2 - Zhao, Zhiwei
A2 - Hao, Fei
A2 - Miao, Wang
PB - Institute of Electrical and Electronics Engineers Inc.
T2 - 18th IEEE International Symposium on Parallel and Distributed Processing with Applications, 10th IEEE International Conference on Big Data and Cloud Computing, 13th IEEE International Symposium on Social Computing and Networking and 10th IEEE International Conference on Sustainable Computing and Communications, ISPA-BDCloud-SocialCom-SustainCom 2020
Y2 - 17 December 2020 through 19 December 2020
ER -